by Case Western Reserve University Credit: Pixabay/CC0 Public Domain Of the roughly 20,000 people in the U.S. diagnosed with esophageal cancer this year, just 4,000 are likely to still be alive in 2027. Such dire data has long driven researchers to try to understand the roots of the disease, but they have discovered little—until now....
Alkaline water: Should you be splurging to make your body less acidic?
by Dr. Michael Daignault, USA Today Credit: CC0 Public Domain As a medical doctor, [I find that] the explosion of interest in alkaline water in recent years has been very concerning. Alkaline water consumption is projected to hit a market capitalization of $1.3 billion by 2023. No doubt this is driven by clever marketing advertising...
New study finds conclusive evidence that head trauma leads to CTE
Kendall Baker Jeff Tracy For the first time, conclusive evidence has been found that repeated head trauma leads to chronic traumatic encephalopathy (CTE), an incurable brain disease. Why it matters: A new study, carried out by nine universities and the Concussion Legacy Foundation, determined athletes in contact sports are 68 times more likely to develop CTE than the...
Study provides better insight into the vagus nerve’s link to the brain
by CU Anschutz Medical Campus Credit: Spencer Bowles et al, Neuron (2022). DOI: 10.1016/j.neuron.2022.06.017 Researchers at the University of Colorado Anschutz Medical Campus have shown a direct link between vagus nerve stimulation and its connection to the learning centers of the brain. The discovery may lead to treatments that will improve cognitive retention in both healthy and...
An Alzheimer’s-defying brain offer clues to treatment and prevention of dementia
by Massachusetts General Hospital Longitudinal tau PET imaging measures in an APOE3ch homozygote. A Surface rendering of tau PET (Flortaucipir) images (standardized uptake value ratio, SUVr), at baseline, 3-year follow-up (center), and B rate of change (expressed as %/year), in the APOE3ch homozygote, (left) a typical PSEN1-E280A impaired carrier (center) and a sporadic AD case (right)....
Could cyber designs deliver potent dual-action antibiotics?
by John Innes Centre Credit: Shutterstock Computational modeling has been used to create dual-action compounds with exciting potential as new antibiotics. The proof of principle experiment raises the possibility of new antibiotics that can target harmful bacteria on two fronts and consequently are less likely to be overcome by resistant strains. The University of Leeds/John...
Coming wave of opioid overdoses ‘will be worse than it’s ever been before’
by Northwestern University A visualization of the data illustrates that between 2019 and 2020, rates of opioid-involved overdose deaths converged while escalating for the first time across six types of rural and urban counties. Credit: Northwestern University Over the past 21 years of opioid overdose deaths—from prescription drugs to heroin to synthetic and semisynthetic opioids...
Teaching an old drug new tricks
by Texas Tech University Sanjay Srivastava, Ph.D., recently received a U.S. patent for repurposing pimavanserin to treat various types of cancer. Credit: TTUHSC To treat some of the psychosis issues associated with Parkinson’s disease, physicians often prescribe pimavanserin, an antipsychotic drug that acts within the brain to prevent hallucinations and delusions. Because of its ability...
Researchers identify specific cells that contribute to the pathology of myasthenia gravis combined with thymus tumor
by Osaka University Proposed MG pathology in thymoma. Credit: Nature Communications (2022). DOI: 10.1038/s41467-022-31951-8 Autoimmune diseases occur when a person’s antibodies mistakenly recognize their body’s own cells as foreign invaders and attack them. One such disease is myasthenia gravis (MG), where the antibodies target neuromuscular-associated proteins. MG is common in patients with thymoma, a type of tumor...
Study gives better understanding of endometriosis and how it grows
by University of Connecticut Credit: Pixabay/CC0 Public Domain The tissue that lines the uterus, known as the endometrium, serves as the location of embryo implantation and the source of the arteries that lead into the placenta to support a fetus during pregnancy. But in humans, when there is no fertilized egg, the endometrium is shed...