COMPUSCRIPT LTD Metabolic-associated fatty liver disease (MAFLD), which is previously known as non-alcoholic fatty liver disease (NAFLD), represents a major health concern worldwide with limited therapy. The authors of this article provide evidence that ferroptosis, a novel form of regulated cell death characterized by iron-driven lipid peroxidation, was comprehensively activated in liver tissues from MAFLD...
Major discovery exposes immune system’s ‘off button’
THE PETER DOHERTY INSTITUTE FOR INFECTION AND IMMUNITY Scientists have discovered what turns off the molecular alarm system that plays a critical role in our immune response. MR1 (MHC class I-related molecule) is an antibacterial superhero – a protein present in every cell of the human body, that acts as a molecular alarm system by...
Fecal transplantation: an effective remedy for life-threatening intestinal infections
AARHUS UNIVERSITY Faeces transplantation in the intestine is an effective cure – and far superior to today’s standard treatment – for a life-threatening infection that affects between 2,500 and 3,000 people in Denmark every year. That is the conclusion of a new study conducted by researchers from Aarhus University and Aarhus University Hospital which has...
Rising food prices hit less-healthy older adults hardest, poll suggests
MICHIGAN MEDICINE – UNIVERSITY OF MICHIGAN IMAGE: THE NATIONAL POLL ON HEALTHY AGING ASKED A NATIONAL SAMPLE OF ADULTS AGE 50 TO 80 HOW RISING FOOD COSTS ARE AFFECTING THEM AND THE HEALTHINESS OF THEIR DIET. THERE WERE KEY DIFFERENCES BASED ON MENTAL HEALTH, PHYSICAL HEALTH, INCOME AND EDUCATION LEVEL CREDIT: UNIVERSITY OF MICHIGAN Three-quarters...
New way to track peripheral artery disease aids quest for better treatments
UNIVERSITY OF VIRGINIA HEALTH SYSTEM IMAGE: UVA HEALTH’S CHRISTOPHER KRAMER, MD, AND COLLABORATORS HAVE DEVELOPED A NEW WAY TO TRACK PERIPHERAL ARTERY DISEASE. CREDIT: DAN ADDISON | UNIVERSITY OF VIRGINIA COMMUNICATIONS Cardiovascular experts at UVA Health have found a new way to track peripheral artery disease (PAD), a serious medical condition involving atherosclerosis in the...
Diets rich in refined fiber may increase liver cancer risk in some individuals
UNIVERSITY OF TOLEDO IMAGE: DR. MATAM VIJAY-KUMAR, LEFT, A PROFESSOR IN THE DEPARTMENT OF PHYSIOLOGY AND PHARMACOLOGY IN THE COLLEGE OF MEDICINE AND LIFE SCIENCES, AND DR. BENG SAN YEOH, A POSTDOCTORAL FELLOW, RECENTLY PUBLISHED A STUDY THAT FOUND DIETS RICH IN HIGHLY REFINED FIBER MAY INCREASE THE RISK OF LIVER CANCER, PARTICULARLY IN INDIVIDUALS...
New UMBC research finds that viruses may have “eyes and ears” on us
UNIVERSITY OF MARYLAND BALTIMORE COUNTY IMAGE: A DELTA BACTERIOPHAGE, THE FIRST IDENTIFIED IN A NEW STUDY IN FRONTIERS IN MICROBIOLOGY TO HAVE BINDING SITES FOR CTRA, A PROTEIN PRODUCED BY THE BACTERIOPHAGE’S HOST THAT REGULATES THE PRODUCTION OF PILI AND FLAGELLA. THE PRESENCE OF THESE BINDING SITES ONLY IN PHAGES THAT REQUIRE THEIR HOST CELLS...
Heart disease prevention is particularly important in cancer patients
by Johannes Angerer, Medical University of Vienna Baseline cardiovascular toxicity risk assessment checklist. BNP, B-type natriuretic peptide; cTn, cardiac troponin; CTR-CVT, cancer therapy-related cardiovascular toxicity; CV, cardiovascular; CVD, CV disease; CVRF, cardiovascular risk factors; ECG, electrocardiogram; eGFR, estimated glomerular filtration rate; HbA1c, glycated hemoglobin; NT-proBNP, N-terminal pro-BNP; TTE, transthoracic echocardiography. Including blood pressure, heart rate,...
New genetically engineered herpes virus kills cancer cells
A genetically modified version of the herpes virus has shown great potential in treating advanced cancers, according to a report by the Institute of Cancer Research in London published on Thursday. A promising therapy Although the treatment is still in early trials, researchers have found that RP2, a modified version of the herpes simplex virus,...
What to do when you’re trying not to poop
Contrary to what some might believe, everybody poops (yes, even women), making it one of the most ordinary and universal human experiences. Bowel movements are an essential part of our digestive health, and they’re really not something you should put off. But sometimes you just can’t get to a toilet. Maybe you’re in the middle...