by Washington University in St. Louis A comprehensive analysis of federal data by researchers at Washington University School of Medicine in St. Louis shows people who have had COVID-19 are at an elevated risk of developing neurological conditions within the first year after infection. Movement disorders, memory problems, strokes and seizures are among the complications....
Research team finds new way to identify ‘safe harbor’ for gene therapies
by St. Jude Children’s Research Hospital A schematic representation of the overall genomic safe harbor identification strategy. a Selection of common pMEIs from healthy individuals with AF > 0.1. b Removing pMEIs significantly associated with gene expression (FDR less than 0.1 in eQTL mapping). c Removing pMEIs showing spatial proximity with oncogenes, tumor suppressor genes,...
Researchers identify potential gene marker for treating pancreatic cancer
by Joe Dangor, Mayo Clinic Credit: Mayo Clinic Researchers at Mayo Clinic Comprehensive Cancer Center have identified a gene marker that may lead to a more effective, precision treatment for pancreatic ductal adenocarcinoma (PDAC). The researcher’s findings are published in Nature Cancer. “Pancreatic ductal adenocarcinoma is one of the most lethal cancers,” says the paper’s senior...
Three things everyone should know about sexually transmitted infections
by University of Colorado at Boulder Credit: Pixabay/CC0 Public Domain Whether you’re in a relationship, hooking up or staying single, knowing how to prevent and treat sexually transmitted infections (STIs) can help you stay healthy and safe. Here are a few things everyone should know about STIs. 1. What are STIs? STIs are infections that pass...
Keeping aggressive cancer cells in check by blocking a protein responsible for repairs
by Catarina Pietschmann, Max Delbrück Center for Molecular Medicine Three-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: NCI Center for Cancer Research, National Cancer Institute, National Institutes of Health Every cell has two mechanisms for repairing DNA single- or double-strand breaks, which...
The way to select a European Better half
European women of all ages are known for their charm and intellect. They are family-oriented and warm. A European woman can help you a man raise a child. She knows how to be a superb mother. And in addition they can also be amazing companions. If you are enthusiastic about meeting a ecu wife, it...
Lasting lung damage seen in children and teens after COVID
by Radiological Society of North America Free-breathing phase-resolved functional lung (PREFUL) low-field MRI at 0.55T with calculated parameters at an axial plane after automatic registration to a mid-expiration position and lung parenchyma segmentation. From left to right, representative color-coded images of functional show ventilation defects (VDP, blue), perfusion defects (QDP, red), ventilation/perfusion (V/Q match, green), ventilation/perfusion...
Researchers advance CRISPR technology to replicate human diseases with unprecedented accuracy
by Walter and Eliza Hall Institute of Medical Research Generation and validation of pdCas9a-SAM construct in Eµ-Myc lymphoma cell lines. a Schematic representation of the pdCas9a-SAM lentiviral construct. b Western blot analysis for BCL-2 in manipulated Eµ-Myc lymphoma cell lines. EMRK-1184 or MRE-721 Eµ-Myc lymphoma-derived cell lines were transduced with pdCas9a-SAM only or pdCas9a-SAM plus Bcl-2...
Rare human gene variant in ADHD, autism exposes fundamental sex differences
by Florida Atlantic University Credit: Pixabay/CC0 Public Domain The prevalence, age of onset, and clinical symptoms for virtually all neuropsychiatric disorders differ between men and women. Among the disorders with pronounced sex bias are Attention-Deficit/Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD), where the ratio of males/females diagnosed is approximately 4 to 1. Whether this skewed...
Aggressive breast cancer linked to African ancestry
by Jane Langille, Cornell University Credit: Pixabay/CC0 Public Domain Weill Cornell Medicine investigators have identified definitive biological links between African ancestry and disease processes that affect an aggressive cancer type called triple-negative breast cancer (TNBC). Their analysis of TNBC tumors from a diverse patient population yielded a large set of genes whose expression differed in patients...