by University of Oxford Credit: University of Oxford Associate Professor Miriam Klein-Flügge and colleagues looked at brain connectivity and mental health data from nearly 500 people. In particular, they looked at the connectivity of the amygdala—a brain region well known for its importance in emotion and reward processing. The researchers used functional magnetic resonance imaging...
The predictive power of blood: Metabolomic profiling reveals risk of multiple diseases all at once
by Stefanie Seltmann, Berlin Institute of Health in der Charité Details of the metabolomic state model. a) Overview of the residual architecture of the metabolomic state model. 168 circulating metabolomic markers are fed to the shared trunk network to learn a common shared representation. Endpoint-specific head networks then predict the metabolomic state for each endpoint...
‘COVID time’ is a real thing, and it’s not good
by Chris Rutkowski, University of Manitoba Credit: Unsplash/CC0 Public Domain Have you ever noticed that time seems to slow down sometimes? Like when you are waiting in line at a bank or grocery checkout, and it just seems to take forever? During the peak of the pandemic, and mid-lockdown, many people reported they felt their days...
Genetically modified herpes virus delivers one-two punch against advanced cancers
by Institute of Cancer Research Carcinoma of salivary gland. Credit: Nephron, CC BY-SA 4.0, via Wikimedia Commons A new genetically engineered virus has delivered a one-two punch against advanced cancers in initial findings from a phase I trial. Researchers found that RP2—a modified version of the herpes simplex virus—showed signs of effectiveness in a quarter...
Transition to newer clot-busting drug improves patient outcomes, lowers cost in treating ischemic stroke
by University of Texas at Austin Tenecteplase works faster, leads to better outcomes & costs about $2500 less per patient, according to new Dell Med study. Credit: Dell Medical School A newer-generation clot-busting drug called tenecteplase outperforms the traditional treatment for ischemic strokes in several key areas, including better health outcomes and lower costs, according...
‘Tremendous hope’: New cystic fibrosis treatment changing lives
“Clubbing” of the fingers is a classic features of Cystic Fibrosis, although not present in many patients. Credit: Jerry Nick, M.D./ Wikipedia David Fiant says his cystic fibrosis and the arduous therapy it required was so bad he “could no longer tell if I was living to heal myself or healing myself to live”. While...
Cell Rover: Exploring and augmenting the inner world of the cell
Michaela Jarvis | MIT Media LabPublication Date: September 22, 2022 PRESS INQUIRIES Caption: An artist’s rendition of the Cell Rover, an intracellular antenna for exploring and augmenting the inner world of the cellCredits:Image: Irakli Zurabishvili for Deblina Sarkar, with models by IronWeber and Lauri Purhonen. Researchers at the MIT Media Lab have designed a miniature...
Emmanuel Mignot wins Breakthrough Prize for discovering cause of narcolepsy
September 22, 2022 – By Nina Bai “I think receiving this Breakthrough Prize is incredible, and I also definitely have the reward of seeing my patients completely changed by these new drugs,” said Emmanuel Mignot. “It’s a fantastic kind of human adventure.”Stanford Medicine photo Emmanuel Mignot, MD, PhD, the Craig Reynolds Professor of Sleep Medicine, is...
The omicron coronavirus variant may protect against flu
By Carissa Wong A coloured scanning electron micrograph of a cell (green) infected with the omicron variant of the coronavirus (purple) NIAID / NATIONAL INSTITUTES OF HEALTH / SCIENCE PHOTO LIBRARY Being infected with the omicron variant of the coronavirus may give some protection against flu. Martin Michaelis at the University of Kent in the UK and his colleagues collected...
Gene mutation discovered that causes language impairment, ADHD and myasthenia
UNIVERSITY OF COLOGNE IMAGE: REPRESENTATIVE IMAGES OF NEURONAL ROSETTES DERIVED FROM CONTROL SAMPLES AND CAPRIN1+/- CELLS. CAPRIN1 PROTEIN (MAGENTA) COULD BE EASILY DETECTED IN THESE STRUCTURES. CREDIT: BRUNHILDE WIRTH, UNIVERSITY OF COLOGNE Two studies have revealed that certain disorders of the CAPRIN1 gene have significant consequences for people. First, the research team showed that insufficient...