by CIC bioGUNE Proteomic analyses reveal changes in hACE2 mouse hepatocytes after infection with pseudotyped viral particles expressing the spike of SARS-CoV-2. a Volcano plot showing the 354 differentially expressed peptides between hACE2 mouse hepatocytes in the presence (+) or absence (−) of pseudotyped viral particles after 48 h. b Volcano plot showing the 132 differentially...
Treating aneurysms with injectable toothpaste-like biomaterials
by Terasaki Institute for Biomedical Innovation Aneurysms are weaknesses in the venous walls that can result in the ballooning and bursting of blood vessels. TIBI scientists have developed an enhanced hydrogel treatment to stop blood flow to the aneurysm until the vessel wall heals. Credit: Terasaki Institute For Biomedical Innovation Aneurysms are weaknesses in the...
Heart attack risk increased among people with HIV and hepatitis C as they aged
by American Heart Association Electron micrographs of hepatitis C virus purified from cell culture. Scale bar is 50 nanometers. Credit: Center for the Study of Hepatitis C, The Rockefeller University. As people with HIV age, their risk of heart attack increases far more if they also have untreated hepatitis C virus, even if their HIV...
COVID deaths: more than 10 million children lost a parent or carer
Jude Coleman Some 7.5 million children have lost one or both parents to COVID-19. Credit: Jaipal Singh/EPA-EFE/Shutterstock Roughly 10.5 million children worldwide have a parent or carer who died from COVID-19, according to a modelling study1. The figure is a dramatic increase on earlier estimates. India, Indonesia and Egypt were the countries most affected; other regions...
Reverse-Engineering the Brain to Decode Input Signals from Output Neuron Firing
Understanding the synchronized responses of neurons in our brain to a common input is key to uncovering how it processes information. But, outside lab experiments, these common inputs are usually unknown. Can this unknown input be reconstructed from output measurements? In a new study, researchers from Japan propose a method that enables this reconstruction based...
Researchers test hybrid, soft/hard nanocarriers to deliver drugs to the brain
IOWA STATE UNIVERSITY IMAGE: IOWA STATE UNIVERSITY AND NANOVACCINE INSTITUTE RESEARCHERS, LEFT TO RIGHT, ANWESHA SARKAR, RIZIA BARDHAN AND DONALD SAKAGUCHI ARE WORKING TO CREATE NANOCARRIERS THAT DELIVER DRUGS ACROSS THE BLOOD BRAIN BARRIER. CREDIT: PHOTO BY CHRISTOPHER GANNON/IOWA STATE UNIVERSITY. AMES, Iowa – Rizia Bardhan made a fist with one hand then covered it...
Radical new treatment system lights up cancer therapy
INSTITUTE OF INDUSTRIAL SCIENCE, THE UNIVERSITY OF TOKYO IMAGE: RESEARCHERS FROM THE INSTITUTE OF INDUSTRIAL SCIENCE, THE UNIVERSITY OF TOKYO HAVE DEVELOPED A STREAMLINED PHOTO-UNCAGING SYSTEM FOR PHOTODYNAMIC CANCER THERAPY, USING A PULSE OF LIGHT FOR TUMOR-SPECIFIC ACTIVATION OF A CANCER-FIGHTING AGENT CREDIT: INSTITUTE OF INDUSTRIAL SCIENCE, THE UNIVERSITY OF TOKYO Tokyo, Japan – One...
Getting Foreign Women of all ages For Matrimony Online
There are many methods to find international women. The online world is an individual http://www.centrodenefrologia.com.br/?p=24805 of the very most popular, and there are several websites out there that help you find your perfect match. meet ghanian women online However , it isn’t always simple to choose the best online dating site. Here are a few...
Cancer research: Key function of important leukemia gene demystified
by Nina Grötschl, University of Veterinary Medicine—Vienna Credit: Pixabay/CC0 Public Domain The oncogene EVI1 causes an aggressive type of leukemia, but its exact function has been a mystery. A research team led by scientists from Vienna now showed that EVI1’s cancer causing effect relies on activating a single gene—the stem cell transcription factor ERG. The...
What lobsters can teach us about immortality
by Maddie Massy-Westropp, University of New South Wales DNA strands coil up into chromosomes, which are capped on the ends by telomeres. Credit: Ian Joson/UNSW No one likes the thought of getting old, but it seems to be an inevitable part of life. Most species grow, develop and repair damage to their bodies until a...