by The Physiological Society Credit: CC0 Public Domain Are you an early bird or a night owl? Our activity patterns and sleep cycles could influence our risk of diseases, such as type 2 diabetes and heart disease. New research published in Experimental Physiology has found that wake/sleep cycles cause metabolic differences and alter our body’s preference for...
by Jeff Hansen, University of Alabama at Birmingham Constitutive activation of JAK1/2 in IFNγR1KO melanoma cells. a Identification of a JAK1/2-centric network of activated protein tyrosine kinases in IFNγR1KO cells by kinomic analysis. Input nodes (kinases) with large blue circles around them and smaller red circles on the top right corner indicate increased activity in IFNγR1KO cells. Arrowheads denote...
by University of Glasgow Credit: Unsplash/CC0 Public Domain New research, led by the University of Glasgow and published in the British Journal of General Practice, assessed patient data from across the U.K. and found that not enough people with chronic kidney disease were routinely being given this recommended test. The study results have prompted renewed calls...
by Ludwig Cancer Research Credit: CC0 Public Domain A team led by Ludwig Lausanne’s Tatiana Petrova, Jeremiah Bernier-Latmani and alum Christoph Cisarovsky identified a novel mechanism by which stem cells in intestinal tumors generate new blood vessels and evade anti-angiogenic therapy. Vascular endothelial growth factor A (VEGFA) is an important supporter of both healthy and...
by Ben Krishna, The Conversation Credit: fizkes/Shutterstock The term “long COVID” is used to describe symptoms or illness that continue for more than four weeks after a positive COVID test or the original onset of symptoms. Some examples include an ongoing loss of taste or smell, debilitating fatigue, and even sustained damage to the heart or brain. Long COVID...
by University of Surrey Credit: Pixabay/CC0 Public Domain Increased levels of exercise could help reduce frailty in patients with the most common form of leukemia, chronic lymphocytic (CLL), according to new research from the University of Surrey. The discovery of a link between frailty and “good cholesterol” (high-density lipoprotein (HDL)) could help identify people most...
by National Research Council of Science & Technology Differences in FAK activation and neuronal protrusion formation in brain tissues of normal and Huntington’s disease patients. Credit: Korea Institute of Science and Technology (KIST) Huntington’s disease (HD) is a hereditary brain disease caused by a mutation in the huntingtin gene. HD is a neurodegenerative disease without...
by Lara Herrero, The Conversation Credit: Pavel Danilyuk/Pexels, CC BY-SA So you’ve had COVID and have now recovered. You don’t have ongoing symptoms and luckily, you don’t seem to have developed long COVID. But what impacts has COVID had on your overall immune system? It’s early days yet. But growing evidence suggests there are changes to your immune...
by Alex Viveros, Broad Institute of MIT and Harvard Small intestine at steady state. Credit: National Institutes of Allergy and Infectious Diseases, National Institutes of Health Trillions of bacteria and other microbes thrive in our gut microbiomes, and over the last decade, scientists have become increasingly aware of the vital role that they play in creating...
by Delthia Ricks , Medical Xpress Credit: Unsplash/CC0 Public Domain Just as bacteria, viruses and fungi develop strategies to outsmart antimicrobial medications, cancer cells can become resistant to chemotherapy. And among tumors, those associated with triple negative breast cancer and ovarian tumors can develop a powerful form of resistance. In an intriguing line of research,...
