by University of Geneva Human pancreatic islet cells with compromised clocks bear decreased membrane lipid fluidity, as compared to the islet cells with functional clocks © 2022. Petrenko et al. (2022) Type 2 diabetes disrupts circadian orchestration of lipid metabolism and membrane fluidity in human pancreatic islets. Credit: PLOS Biology (2022). DOI: 10.1371/journal.pbio.3001725 Like all living beings, human...
by American Institute of Physics Dr. Samantha Kleindienst Robler taking a photo of an ear (not a patient) using a telemedicine cart. Credit: Reba Lean According to the World Health Organization, 1.6 billion people across the globe are living with hearing loss. Much of that is preventable, stemming from excessive noise, untreated ear infections, and...
by American Heart Association Overview of study sample and sex distribution of emergency department (ED) cardiovascular presentations. *Arrows indicate relative frequency of risk factor (eg, there were more smokers among men than women). AA indicates aortic aneurysm; AF, atrial fibrillation; AMI, acute myocardial infarction; CKD, chronic kidney disease (hypertensive); CVD, cardiovascular disease; DVT, deep vein...
by The Mount Sinai Hospital Credit: Pixabay/CC0 Public Domain Scientists from The Tisch Cancer Institute have uncovered a mechanism by which certain breast cancer cells regulate their own metastases, fuel dissemination from the original tumor site, and determine routes to invade distant organs such as the lungs, according to a study published in Cell Reports in September....
by Cynthia McCormick Hibbert, Northeastern University Neel Joshi, associate professor of chemistry and chemical biology, is a lead author in a PLOS Pathogens paper that could lay ground for probiotic pill to prevent childhood diarrhea, a leading cause of infant mortality around the globe. Credit: Ruby Wallau/Northeastern University Across much of the world, childhood diarrhea is a major...
by Ludwig Cancer Research Graphical abstract. Credit: Molecular Cell (2022). DOI: 10.1016/j.molcel.2022.04.010 A team led by Ludwig Stanford’s Laura Attardi explored novel mechanisms by which the p53 protein, often called the guardian of the genome, regulates gene expression by looking for novel proteins that interact with the versatile tumor suppressor in response to cellular stressors. The researchers...
by American Physiological Society Credit: CC0 Public Domain New research identifies the importance of the protein adropin in preventing stiffness in the arteries of people with obesity and type 2 diabetes. The study is published ahead of print in the American Journal of Physiology-Heart and Circulatory Physiology. Arterial stiffness is a condition associated with aging and...
by Ludwig Cancer Research Graphical abstract. Credit: Cell (2022). DOI: 10.1016/j.cell.2022.03.030 Natural killer (NK) cells have lately become a hot focus of efforts to develop new immunotherapies. Researchers led by Ludwig Harvard’s Tony Letai, whose team collaborated closely with the Ludwig Harvard Kai Wucherpfennig lab in this study, reported in an April issue of Cell a potentially novel approach...
by Pennsylvania State University Credit: Unsplash/CC0 Public Domain “Young” and “athletic” aren’t adjectives often mentioned in the same sentence as vascular surgery, but that’s the crazy thing about thoracic outlet syndrome. The disease strikes young people—often patients in their 20s and 30s—and the usual culprits of vascular disease like diabetes, high cholesterol and high blood pressure...
by Institute of Cancer Research Cancer cell being attacked by two immune cells. Credit: NIH Image Gallery, CC BY 2.0 DNA damage is one of the foundational causes of cancer. But researchers have now found that deliberately causing DNA damage—by delivering additional treatments like radiotherapy—could improve the effectiveness of immunotherapy for some people with kidney...
