by Johns Hopkins University School of Medicine Cutaway view (left) of SARS-CoV-2, the virus that causes COVID-19, showing its double stranded RNA genome. During infection, the virus takes over a host cell’s DDX3 RNA helicase protein (right) to unwind the viral RNA and enable it to be copied. A new study shows that a Johns...
New antibody shows therapeutic effects in mice with Alzheimer’s disease
by University of Texas Health Science Center at Houston Credit: Pixabay/CC0 Public Domain A newly developed agonistic antibody reduced the amyloid pathology in mice with Alzheimer’s disease, signaling its promise as a potential treatment for the disease, according to a team of researchers at UTHealth Houston. Research led by senior author Zhiqiang An, Ph.D., professor...
Study finds damage in the lungs of chronic e-cigarette users
by McKenzie Ridings, Massachusetts General Hospital Credit: CC0 Public Domain Chronic use of e-cigarettes, commonly known as vaping, can result in progressive small airway obstruction and asthma-like symptoms such as shortness of breath and chest pains, according to researchers at Massachusetts General Hospital (MGH). In the first study to microscopically evaluate the pulmonary tissue of...
How to deal with sleep problems during heat waves
by Wiley Credit: CC0 Public Domain With heatwaves occurring more frequently, investigators from the European Insomnia Network recently explored how outdoor nighttime temperature changes affect body temperature and sleep quality. Their review of the literature, which is published in the Journal of Sleep Research, indicates that environmental temperatures outside the thermal comfort can strongly affect human...
Three-drug combination slows progression of advanced kidney cancer
by Dana-Farber Cancer Institute Credit: CC0 Public Domain A targeted kinase inhibitor added to a two-drug immunotherapy combination slowed the progression of advanced kidney cancer in previously untreated patients, according to research led by an oncologist from Dana-Farber Cancer Institute. “Patients who received the kinase inhibitor cabozantinib in addition to checkpoint-blockers nivolumab and ipilimumab experienced...
Study finds connection between COVID and new-onset AFib
by American Heart Association Credit: Pixabay/CC0 Public Domain A study in the American Heart Association journal Circulation: Arrhythmia and Electrophysiology finds new-onset atrial fibrillation (AFib) in 1 in 20 patients hospitalized with COVID-19. AFib is a quivering or irregular heartbeat (arrhythmia) that can lead to blood clots, stroke, heart failure and other heart-related complications. At...
Chlamydia’s stealthy cloaking device identified
by Duke University At left: A wild type Chlamydia (green) surrounded by the GarD protein (red) that cloaks it from detection inside human cells. Right: Chlamydia with GarD knocked out (green) are enveloped by the antimicrobial proteins ubiquitin (yellow) and RNF213 (magenta). Credit: Stephen C. Walsh, Duke University Chlamydia, the leading cause of sexually transmitted...
Researchers discover potential treatment for Chagas disease
by Leigh Beeson, University of Georgia The new drug works by targeting the parasite that causes Chagas disease, Trypanosoma cruzi, which is carried by kissing bugs like the one shown above. Credit: CDC Researchers from the University of Georgia have discovered a potential treatment for Chagas disease, marking the first medication with promise to successfully...
Meditation holds the potential to help treat children suffering from traumas, difficult diagnoses or other stressors
by Hilary A. Marusak, The Conversation Credit: CC0 Public Domain Children actively meditating experience lower activity in parts of the brain involved in rumination, mind-wandering and depression, our team found in the first brain-imaging study of young people under 18 years old. Over-activity in this collection of brain regions, known as the default mode network, is thought to...
“Universal” pathway behind cell recycling offers clues to combat aging
By Nick Lavars September 08, 2022 In this fluorescence microscopy image, the endoplasmic reticulum network seen in green wraps around damaged lysosomes seen in redJay Xiaojun Tan Sometimes called the cellular recycling system, lysosomes are tiny structures that break down and clear away molecular waste to keep cells young and fresh. For this reason, they...