by Zhejang University Figure1: The novel peripheral blood nerve-derived extracellular vesicle-related marker. Credit: NMDAR2A Alzheimer’s disease (AD) is characterized by a decline in cognitive function, memory loss, and in severe cases, language impairment, and ultimately the loss of independent living ability. According to estimates by Chinese Center for disease Control and Prevention, there are about...
Megan Brooks September 02, 2022 The US Food and Drug Administration (FDA) has approved the biologic agent spesolimab (Spevigo) for the treatment of flares in adults with generalized pustular psoriasis (GPP), the company has announced. “GPP flares can greatly impact a patient’s life and lead to serious, life-threatening complications,” Mark Lebwohl, MD, principal investigator in the pivotal...
Blood oxygen level is the amount of oxygen circulating in the blood. Red blood cells carry most of the oxygen, collecting it from the lungs and delivering it to all parts of the body. The body closely monitors blood oxygen levels to keep them within a specific range so that there is enough oxygen for...
New research provides insight into how an important class of molecules are created and moved in human cells. For years, scientists knew that mitochondria – specialized structures inside cells in the body that are essential for respiration and energy production – were involved in the assembly and movement of iron-sulfur cofactors, some of the essential compounds...
by Edith Cowan University Transcranial random noise stimulation (tRNS). A) An example of a tRNS electrode montage and its modeled electrical field strength (normE) targeting the visual cortex. B) A random level of current is generated for every sample (sampling rate 1280 Hz). The random numbers are from a normal distribution and the average current applied...
by Tel Aviv University Dr. Lior Mayo and students. Credit: Tel Aviv University A groundbreaking study at Tel Aviv University effectively eradicated glioblastoma, a highly lethal type of brain cancer. The researchers achieved the outcome using a method they developed based on their discovery of two critical mechanisms in the brain that support tumor growth and...
by Matthew Woodruff, The Conversation Credit: Unsplash/CC0 Public Domain For almost three years, scientists have raced to understand the immune responses in patients who develop severe COVID-19, with an enormous effort aimed at defining where healthy immunity ends and destructive immunity begins. In the early days of the COVID-19 pandemic, much attention focused on reports of harmful inflammation and so-called cytokine...
by New York Genome Center The graphical abstract of the study. Credit: Marta Byrska-Bishop (New York Genome Center) Seven years ago, the 1000 Genomes Project (1kGP) published an open-access resource based primarily on low-coverage whole-genome sequencing (WGS) data of 2,504 individuals from 26 populations representing five continental regions of the world, making it the first...
by Washington University School of Medicine A new study from Washington University School of Medicine in St. Louis suggests a simple blood test—administered before CAR-T cell treatment is initiated—may identify which patients are predisposed to developing neurotoxic side effects after CAR-T cell therapy. Severe side effects can include seizures, brain swelling and strokes. Evidence of a...
One in five migraine patients has multiple chemical sensitivity (MCS), according to a study recently published in the Journal of Occupational Health. Keisuke Suzuki, M.D., Ph.D., from Dokkyo Medical University in Mibu, Japan, and colleagues examined the relationship between MCS and migraine using data from 95 consecutive patients in an outpatient headache clinic. Headache-related disability was...
