by Public Library of Science Credit: Pixabay/CC0 Public Domain Researchers have developed a new method to identify people who are at greater genetic risk of developing Alzheimer’s disease before any symptoms appear—which could help speed creation of novel treatments. Manish Paranjpe of the Broad Institute of MIT and Harvard in Cambridge, Massachusetts, United States, and...
by St. Jude Children’s Research Hospital Graphic abstract. Credit: Cell (2022). DOI: 10.1016/j.cell.2022.07.025 Scientists at St. Jude Children’s Research Hospital have identified how some cancer cells cheat treatment-induced cell death. In doing so, they persist and lead to cancer recurrence. The findings may serve as the basis for drugs that prevent relapses by inhibiting cancer cells from...
by University of Cambridge Credit: Pixabay/CC0 Public Domain Adult and adolescent cannabis users are no more likely than non-users to lack motivation or be unable to enjoy life’s pleasure, new research has shown, suggesting there is no scientific basis for the stereotype often portrayed in the media. Cannabis users also show no difference in motivation...
UNIVERSITY OF EASTERN FINLAND In the young population, arterial stiffness, an emerging risk factor for hypertension, indirectly raises blood pressure via an increase in insulin resistance but not via an increase in body fat, a paper published in Frontiers in Cardiovascular Medicine concludes. There is a global effort aimed at screening, identification, and early diagnosis of hypertension...
by University of Granada Visual abstract. Credit: JAMA Network Open (2022). DOI: 10.1001/jamanetworkopen.2022.27893 Is it possible to make humans smarter? There has been a traditional belief that intelligence is a characteristically stable trait; however, in recent years this conception has begun to change. Intelligence may be more modifiable than previously thought. While there are well-known benefits of...
by Leiden University The yellow-red color marks the seed region, the green color demonstrates negative functional interactions, and the blue color demonstrates positive functional interactions. Panel A demonstrates the left IPC caudal cluster functional connectivity when switching to L1 and panel B shows the right IPC caudal cluster functional association under the same condition. Credit: NeuroImage (2022)....
by Institut National de la Sante et de la Recherche Medicale Credit: CC0 Public Domain An Inserm team at the Lille Neuroscience & Cognition laboratory (Inserm/Université de Lille, Lille University Hospital) has joined forces with its counterparts at Lausanne University Hospital (CHUV) to test the efficacy of GnRH injection therapy in order to improve the...
by Emily Moskal, Stanford University Credit: Pixabay/CC0 Public Domain Numbers tell a story. From your credit score to your age, metrics predict a variety of outcomes, whether it’s your likelihood to get a loan or your risk for heart disease. Now, Stanford Medicine researchers have described another telling metric—one that can predict mortality. It’s called...
by LAURA UNGAR This microscope photo provided by the Mayo Clinic in August 2022 shows senescent myoblast cells. Senescent cells resist apoptosis, or programmed cell death, and characteristically get big and flat, with enlarged nuclei. They release a blend of molecules, some of which can trigger inflammation and harm other cells — and paradoxically also...
by Sarah Avery, Duke University Graphical abstract. Credit: Cell Reports (2022). DOI: 10.1016/j.celrep.2022.111268 In animal studies led by researchers at Duke Cancer Institute, a drug approved to treat leukemia successfully disrupted the ability of HER2-positive breast cancer tumors from colonizing the brain. The finding, appearing online Aug. 30 in the journal Cell Reports, provides evidence for human trials and...
