by Michael Merschel, American Heart Association News “How do you feel about black licorice?” sounds like a question for starting a simple chat at a Halloween party—or a silly internet fight. It’s a love-it-or-hate-it candy that inspires intense opinions. But if you ask a health expert, expect a serious conversation—because eating lots of black licorice...
by Wolters Kluwer Health Graphical abstract. Credit: Journal of Urology (2022). DOI: 10.1097/JU.0000000000002928 The standard cutoff point for low testosterone levels may not be accurate for men in their mid-forties and younger, reports a study in the Journal of Urology. “Young men have different testosterone reference ranges than older men,” comments lead author Alex Zhu, DO, of University...
by Catherine Caruso, Harvard Medical School a Ganglioside degradation pathway in the lysosome. The names of glycosyl hydrolases (green), activator proteins (purple), and associated metabolic diseases (red) are indicated in the scheme. b Quantification of mono-sialyated and di-sialyated ganglioside species isolated from Grn+/+ (gray) (n = 6), Grn+/R493X (blue) (n = 4), and GrnR493X/R493X (purple) (n = 4) mouse brains. c...
UNIVERSITY OF CALIFORNIA – SAN DIEGO IMAGE: MARK TUSZYNSKI, MD, PHD, IS A PROFESSOR OF NEUROSCIENCES AND DIRECTOR OF THE TRANSLATIONAL NEUROSCIENCE INSTITUTE AT UC SAN DIEGO SCHOOL OF MEDICINE. CREDIT: UC SAN DIEGO HEALTH SCIENCES In recent years, researchers have made measurable progress, using animal models, to promote tissue regeneration in spinal cord injuries...
by CU Anschutz Medical Campus Credit: CC0 Public Domain Scientists investigating why people who have had shingles are at a higher risk of stroke, now believe the answer lies within lipid vesicles called exosomes that shuttle proteins and genetic information between cells, according to new research from the University of Colorado Anschutz Medical Campus. The...
by George Institute for Global Health Credit: CC0 Public Domain A large stroke trial has shown that intensive blood pressure lowering after clot removal worsens recovery. The results of the trial, stopped early due to the significance of the findings, were presented in a late-breaking session at the World Stroke Congress and simultaneously published in The...
by Monash University Credit: Pixabay/CC0 Public Domain Sleep strategies and simple bedtime routines can improve sleep in autistic children, reducing anxiety and enhancing family well-being, a new study reveals. The largest study of its kind into sleep problems in children on the autism spectrum, led by Monash University’s Professor Nicole Rinehart, found clinician-led behavioral interventions helped kids get...
by Sarah Avery, Duke University Two doses of RBD-scNP vaccination protected mice from challenges of SARS-CoV-2 variants and other betacoronaviruses. a Schematic of the mouse challenge studies. 11-month-old female BALB/c mice (n = 10 per group) were immunized intramuscularly twice with adjuvanted RBD-scNP and challenged with SARS-CoV-2 mouse-adapted 10 (MA10) WA-1, SARS-CoV-2 MA10 Beta variant, SARS-CoV-1 mouse-adapted...
by University of Seville Schematic model of the regulation and role of RNAPII-generated nascent RNA to guide DNA end resection and DSB repair by HR. Credit: Nature Communications (2022). DOI: 10.1038/s41467-022-33027-z RNA, the molecule that gave rise to life, has been shown to be essential for repairing human genetic material and preventing mutations that might lead to...
by La Jolla Institute for Immunology The image on the left shows an eight-cell blastomere developed from mouse embryonic stem cells with normal TET function. The image on the right shows the consequences of TET deletion (triple knockout). This blastomere shows signs of aneuploidies and chromosome segregation defects. Credit: Rao Lab, La Jolla Institute for...
