Pauline Anderson November 16, 2022 Acupuncture is associated with significant, long-term reduction in joint pain for postmenopausal women with early breast cancer who experience aromatase inhibitor (AI)–related arthralgias, new research shows. In a multicenter study with more than 200 participants, results showed that for patients who received a 12-week acupuncture intervention, joint pain was reduced for up...
Month: <span>November 2022</span>
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Dangerous parasite that can infect people now found in U.S. foxes
by Amy Norton A rare parasitic disease that has long been documented in Europe seems to have taken root in the United States. Researchers in Vermont are reporting on two human cases of the disease, called alveolar echinococcosis (AE), which were caused by a European strain of the parasite E. multilocularis. They also found evidence of...
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Researchers discover new oral drug for lowering cholesterol
by University Hospitals Cleveland Medical Center Graphical abstract. Credit: Cell Reports (2022). DOI: 10.1016/j.celrep.2022.111538 After statins, the next leading class of medications for managing cholesterol are PCSK9 inhibitors. These highly effective agents help the body pull excess cholesterol from the blood, but unlike statins, which are available as oral agents, PCSK9 inhibitors can only be administered as...
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Association between diabetes medication and less severe cases of COVID-19
by University of Minnesota Medical School Credit: Pixabay/CC0 Public Domain Published in PLOS ONE, a study led by the University of Minnesota Medical School studied adults with type 2 diabetes who were taking metformin, a commonly prescribed diabetes medication. Researchers found an association with less severe cases of COVID-19 for those prescribed metformin. These findings were...
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Down syndrome, like Alzheimer’s, is a double-prion disorder
by University of California, San Francisco PET scan of a human brain with Alzheimer’s disease. Credit: public domain The brains of people with Down syndrome develop the same neurodegenerative tangles and plaques associated with Alzheimer’s disease and frequently demonstrate signs of the neurodegenerative disorder in their forties or fifties. A new study from researchers at...
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Blinding eye disease strongly associated with serious forms of cardiovascular disease
by The Mount Sinai Hospital The abnormal subretinal drusenoid deposits (SDDs) are the multiple, gray, conical lesions (yellow arrows) sitting on top of the bright white band known as the retinal pigment epithelium (RPE). They are pushing and penetrating the thin white retinal layer above them. All the other retinal layers further above are normal....
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MAP3K15 variant found to be a potential target for managing diabetes
by Bob Yirka, Medical Xpress MAP3K15 quantitative trait and disease signatures. (A) Genes with the most similar quantitative trait profiles to MAP3K15 in the UKB, derived from Gene-SCOUT. (B) Linear regression coefficients for HbA1c and glucose from collapsing analysis models for genes in (A) (genes are sorted from top to bottom in decreasing order of...
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The protein behind immunotherapy resistance
by Ecole Polytechnique Federale de Lausanne Tumor with FMRP-deficient cancer cells (in green) being infiltrated and attached by killer (CD8) T cells. Credit: Jeremy Guillot (Hanahan Lab – EPFL). Immunotherapy is a cutting-edge approach to treating cancer by turning the patient’s own immune system against their tumor. Our increasing knowledge of the mechanisms by which...
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Protein signature identifies those at highest risk from severe infection
by The Francis Crick Institute Graphical abstract. Credit: Immunity (2022). DOI: 10.1016/j.immuni.2022.11.007 Scientists at the Francis Crick Institute have uncovered how a build-up of DNA molecules can impact survival chances in people with severe COVID-19 or sepsis, and have developed a tool that could be used to identify the patients at most risk. Chromatin is a complex...
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Novel Intervention Relieves Depression in MS Patients
Kelli Whitlock Burton November 07, 2022 An internet-based cognitive-behavioral therapy (iCBT) program specifically designed for patients with multiple sclerosis (MS) significantly reduced depressive symptoms compared to usual treatment, new research shows. Participants in the randomized controlled trial who received iCBT either alone or in combination with weekly emails from therapists reported benefits that persisted up...