by Johns Hopkins University School of Medicine Schematic showing DRP-104’s bio-activation to DON in tumor and bio-inactivation to an inert metabolite in GI tissues. Credit: Jennifer E. Fairman, CMI, FAMI, Department of Art as Applied to Medicine Johns Hopkins Medicine researchers have revamped an anti-cancer drug to better target cancer cells and leave healthy tissues...
by Washington University School of Medicine Red and orange areas on these heat maps of human brains show where the gene APOE is most active (top two brain images) and where tangles of the protein tau are most concentrated (bottom two brain images). APOE is the biggest genetic risk factor for Alzheimer’s, and tau tangles...
by CU Anschutz Medical Campus ENI ablates the immune response to combined radiation and immunotherapy. A Schematic of the experimental design for gross tumor irradiation with or without elective nodal irradiation (ENI). Mice were implanted both in the buccal and in the flank on day 0 post-implantation (DPI). Stereotactic body irradiation (SBRT) was given when...
Paul Schloesser Associate Editor Humira is the best selling drug of all time. And as biosimilars for the drug venture onto the open market in Jan. 2023, one of the big three PBMs is making room for the biosimilars to compete on equal footing with the brand-name version. UnitedHealth Group’s PBM OptumRx — one of...
By Jonathan Wosen Nov. 16, 2022 The Pfizer/BioNTech Covid-19 vaccines use mRNA technology. CHRISTOPHE ENA/POOL/AFP VIA GETTY IMAGES This story has been adapted from the STAT Report “The future of messenger RNA: Covid-19 vaccines are just the beginning.” While billions of vaccine doses administered during the pandemic have generated reams of data about the safety and effectiveness...
By Nicholas Florko Nov. 16, 2022 ALEX HOGAN/STAT WASHINGTON – The Food and Drug Administration is formally warning multiple companies they must stop selling vapes and other products marketed to young people, including two that STAT highlighted in recent reporting on the industry. STAT reported in August that Wizman Limited, one of the companies FDA warned Wednesday, was...
By Lev Facher Nov. 16, 2022 Packets of buprenorphine ELISE AMENDOLA/AP Doctors are reporting a troubling trend when it comes to fentanyl. The powerful drug, they say, isn’t just causing overdoses — it’s also making it more difficult to begin addiction treatment. In particular, fentanyl appears more likely to cause severe withdrawal symptoms for patients put...
Tara Haelle November 15, 2022 The blood test is one of the most common medical labs performed to understand what is going on with a person’s health. But the test requires taking blood with a needle, which only trained health care professionals can do before sending the sample off to a lab for analysis. Now, researchers have...
by Public Library of Science Preparation of ayahuasca (from B. caapi and P. viridis). Credit: Daniel Perkins, CC-BY 4.0 (creativecommons.org/licenses/by/4.0/) There is a high rate of adverse physical effects and challenging psychological effects from using the plant-based psychoactive ayahuasca, though they are generally not severe, according to a new study by Daniel Perkins of University...
By Devin Tomb Photo-Illustration: The Cut; Photos: Getty, Ozempic This article was featured in One Great Story, New York’s reading recommendation newsletter. You might love this so-called miracle drug. After a month or two on .25 milligrams, the typical starter dose for Ozempic, you may notice that your jeans fit better. You may notice everything...
