by European Society of Cardiology Credit: European Journal of Preventive Cardiology (2022). DOI: 10.1093/eurjpc/zwac239 Morning physical activity is associated with the lowest risk of heart disease and stroke, according to a study in more than 85,000 individuals published today in the European Journal of Preventive Cardiology. The findings were consistent regardless of the total amount of daily activity....
by University of Texas at Dallas A short term HFD regime does not induce the development of obesity nor hyperglycemia. (a) Mice were assigned either a HFD or chow diet at 6 weeks of age for 9 weeks. Weight assessment was performed weekly and blood glucose measurements were performed every weeks starting at week zero....
by Xochitl Rojas-Rocha, University of California – San Diego The custom design allows for free movement without distorting the adhesiveness and robustness of the physical structure of the electrode array. (a) The custom surface electrode array is adhesive integrated, flexible, and non-invasively attached to the subject’s anterior cervical neck, placed lateral to the trachea and...
by University of Maryland School of Medicine The brain’s claustrum activates when a person performs a complicated task. Credit: Brian Mathur, UMSOM Tucked underneath the brain’s outer, wrinkly cortex is a deeply mysterious area, known as the claustrum. This region has long been known to exchange signals with much of the cortex, which is responsible...
by Ingrid Fadelli, Medical Xpress GFAP immunostaining of an iPSC-derived astrocyte displaying a stellate ramified morphology in co-culture with iPSC-derived neurons (not visualized). Credit: Leng et al. Astrocytes or astroglia, the largest glial cell population in the central nervous system (CNS), perform numerous vital functions. Among other things, these glial cells (i.e., cells supporting functions...
by Li Yuan, Chinese Academy of Sciences Mapping secretome-mediated interaction between paired neuron-macrophage single cells. Credit: Deng Jiu Neuron cells are directly associated with neurodegenerative diseases. However, they are not isolated. They interact/communicate with surrounding cells through physical contact, the signal-ligand pathway, and other means to realize neural functions cooperatively. Recent studies have shown that...
By UNIVERSITY OF HOUSTON NOVEMBER 14, 2022 Researchers report the breakthrough discovery of a new vaccine that targets the dangerous synthetic opioid fentanyl. It can block fentanyl’s ability to enter the brain, thus eliminating the drug’s “high.” Study suggests new vaccine could prevent deadly opioid from entering the brain. A new vaccine has been developed that targets...
BY QUINN PHILLIPS | NOVEMBER 10, 2022 Family doctors may be effective at identifying diabetic retinopathy despite not being eye specialists, according to the results of a new study designed to test their ability to do so. The study was presented at 2022 meeting of the American Academy of Ophthalmology, and described in an article at Healio. Diabetic...
by University of Oxford Inhibition of glucokinase prevents the effects of chronic hyperglycaemia. a Schematic showing how mannoheptulose (MH) inhibits glucose metabolism. b, c Insulin secretion (b) and insulin content (c) in LG-cells and HG-cells cultured for 48 h ± 10 mM mannoheptulose (MANNO) and then stimulated with 2 mM or 20 mM glucose. Mannoheptulose was omitted during the assay (n = 3...
by ByTerri Malloy, Mayo Clinic Study participant engagement with the customized Mayo Clinic iPhone application. Credit: Nature Medicine (2022). DOI: 10.1038/s41591-022-02053-1 A study published in Nature Medicine reports the ability of a smartwatch ECG to accurately detect heart failure in nonclinical environments. Researchers at Mayo Clinic applied artificial intelligence (AI) to Apple Watch ECG recordings to identify patients with...
