by Dana-Farber Cancer Institute Graphical abstract. Credit: Cancer Cell (2022). DOI: 10.1016/j.ccell.2022.10.017 For many patients with a condition that often precedes multiple myeloma, early treatment can slow or delay the progression to myeloma. In a new study, investigators at Dana-Farber Cancer Institute demonstrate that changes in immune system cells can indicate which patients with high-risk “smoldering” myeloma...
UNIVERSITY OF WÜRZBURG IMAGE: DIMERIC STRUCTURE OF PHOSPHOGLYCOLATE PHOSPHATASE. THE ENLARGED SECTION ON THE RIGHT SHOWS THE LIGAND-BINDING POCKET IN COMPLEX WITH THE SMALL MOLECULE INHIBITOR CP1. CREDIT: NATALIA YUAN-CHEN As differently as cancers or autoimmune diseases such as multiple sclerosis, rheumatoid arthritis or psoriasis affect people – they all have one characteristic in common:...
AARHUS UNIVERSITY IMAGE: THE MAIN ACTORS BEHIND THE STUDY ARE (FROM LEFT) PROFESSOR JENS LEIPZIGER OF THE DEPARTMENT OF BIOMEDICINE AT AARHUS UNIVERSITY, CONSULTANT SØREN JENSEN-FANGEL, CONSULTANT MAJBRITT JEPPESEN AND CONSULTANT PEDER BERG FROM AARHUS UNIVERSITY HOSPITAL. PHOTO: AU CREDIT: AARHUS UNIVERSITY Researchers have developed a simple urine test to measure the severity of the...
UNIVERSITY AT BUFFALO BUFFALO, N.Y. — For people with multiple sclerosis (MS), hearing a doctor tell them they are experiencing brain atrophy — an important, predictive biomarker of MS disease progression — can trigger debilitating fear and anxiety. Now a team of University at Buffalo researchers working alongside people with MS and their advocates has...
HOSPITAL FOR SPECIAL SURGERY Investigators at Hospital for Special Surgery (HSS) have discovered that at the time of total knee replacement, women have significantly increased levels of immune cells called mast cells in synovial tissue surrounding the knee joint than men. Their findings, presented today at the annual meeting of the American College of Rheumatology, ACR...
TECHNION-ISRAEL INSTITUTE OF TECHNOLOGY Researchers at the Technion – Israel Institute of Technology have developed a technique to measure the long-term effects of antibiotic combinations, or cocktails. These combinations are of serious interest to the scientific and medical communities because the use of single antibiotics often leads to the rapid development of bacterial resistance to...
by Society of Nuclear Medicine Patients with newly diagnosed breast cancer receive a PET/MRI scan to investigate axillary lymph node involvement. The radiologist then assesses whether lymph node involvement is present (nodal positive vs. nodal negative) based on easily assessable morphological and metabolic lymph node criteria. Based on these data, a random forest model is...
by Rockefeller University Credit: Pixabay/CC0 Public Domain As a rare and lethal liver cancer that disproportionately harms young adults, fibrolamellar carcinoma is nearly incurable. Surgery can remove the tumor, but no existing therapies are capable of reining in the cancer once it starts to spread throughout the body. Now, a new study demonstrates that fibrolamellar...
by Noah Fromson, University of Michigan Credit: Justine Ross, Michigan Medicine Everyone ages at a different pace. That’s why two 50-year-olds, despite living the same number of years, may have different biological ages—meaning that a host of intrinsic and extrinsic factors have caused them to age at varying paces with different levels of risk for...
If red wine and dark chocolate prevent cancer or heart disease, it is not, as was suspected, because of the antioxidant resveratrol. Italians who consume lots of an antioxidant found in red wine, dark chocolate, and berries don’t outlive those who ingest smaller amounts and are just as likely to develop cardiovascular disease or cancer,...
