by Cindy Krischer Goodman Credit: Pixabay/CC0 Public Domain Florida doctors are using a new test to determine someone’s future risk for Alzheimer’s disease from a few drops of spit. At a time when the disease’s prevalence is rising, the saliva test called genoSCORE analyzes more than 114,000 different genes to provide a score of 0 to 1...
by Mariah Chuprinski, Pennsylvania State University Wenyu Tu, co-author on the eLife paper and doctoral student in neuroscience in the Huck Institutes of the Life Sciences, sets up a functional MRI experiment. Functional MRI was used in conjunction with neuronal electrophysiology to identify a link between respiration and neural activity changes. Credit: Kelby Hochreither/Penn State Mental...
by European Alliance of Associations for Rheumatology (EULAR) Flow chart. ACR, American College of Rheumatology; bDMARDs, biological disease-modifying antirheumatic drugs; csDMARDs, conventional synthetic DMARDs; FDA, Food and Drug Administration; JAK, Janus kinase; MTX, methotrexate; NMSC, non-melanoma skin caner; tsDMARDs, targeted synthetic DMARDs. Credit: Annals of the Rheumatic Diseases (2022). DOI: 10.1136/ard-2022-223356 Since their first publication...
by University of Wisconsin-Madison This schematic illustration shows probiotic bacteria (teal) coated in a layer of biomaterial as they travel through a human intestine. Attached to the bacteria are reactive oxygen species nano-scavengers. Credit: Quanyin Hu Like elite firefighters headed into the wilderness to combat an uncontrolled blaze, probiotic bacteria do a better job quelling...
TOKYO UNIVERSITY OF SCIENCE IMAGE: INTRANASAL ADMINISTRATION OF PAS-CPP-GLP-2 RESULTS IN ITS DELIVERY TO THE BRAIN VIA TRIGEMINAL AXONS OF THE TRIGEMINAL NERVES. THEREFORE, IT IS THOUGHT TO CONSTITUTE A NERVE-ASSOCIATED TRANSCELLULAR PATHWAY FOR DRUG DELIVERY. CREDIT: PROF. CHIKAMASA YAMASHITA FROM TOKYO UNIVERSITY OF SCIENCE Intranasal (in.) administration has been garnering increasing popularity as a...
by Cheryl Critchley, Monash University Credit: Pixabay/CC0 Public Domain A Monash University-led trial of a new drug known as Q-122 therapy significantly reduced the number and severity of hot flashes and night sweats in women who have been diagnosed with breast cancer. It also improved their sleep and had no serious adverse effects. QUE Oncology’s...
by McGill University Credit: CC0 Public Domain The World Health Organization’s most recent estimates (2016) are that over 4.2 million people die prematurely each year due to long-term exposure to fine particulate outdoor air pollution (often referred to as PM2.5). A recent study involving McGill researchers now suggests that the annual global death toll from outdoor PM2.5...
TOKYO MEDICAL AND DENTAL UNIVERSITY IMAGE: USUALLY, BLOOD VESSELS ARE STABILIZED, AND THEIR BARRIER FUNCTION IS MAINTAINED BY THE TIGHT ADHESION BETWEEN VASCULAR ENDOTHELIAL CELLS (①). WHEN CANCER CELLS METASTASIZE TO DISTANT ORGANS VIA BLOOD VESSELS, THE MORPHOLOGY OF VASCULAR ENDOTHELIAL CELLS CHANGES IN RESPONSE TO THE GROWTH FACTORS OR CYTOKINES SECRETED BY THE CANCER...
by University of Cambridge Credit: CC0 Public Domain Scientists have used a proteomics approach to identify a three-protein signature in the blood that can improve detection of isolated impaired glucose tolerance, a form of prediabetes. The research, led by scientists from the Medical Research Council (MRC) Epidemiology Unit at the University of Cambridge, U.K., and Berlin...
by Aalto University Joonas Laurinoja (in the middle) plans to use the device in his own project in the field of magnetic resonance imaging. Matilda Makkonen on the left and Ida Granö on the right. Credit: Mikko Raskinen Clinicians and researchers have long used transcranial magnetic stimulation (TMS) to treat and study chronic pain and severe...
