Month: <span>November 2022</span>

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Unlocking a decades-long mystery that has hampered development of a walking pneumonia vaccine
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Unlocking a decades-long mystery that has hampered development of a walking pneumonia vaccine

UNIVERSITY OF CONNECTICUT IMAGE: ASSOCIATE PROFESSOR STEVEN SZCZEPANEK (STANDING, LEFT) WITH GRADUATE STUDENTS TYLER GAVITT (SEATED) AND ARLIND MARA (STANDING, RIGHT). CREDIT: JASON SHELDON/UCONN PHOTO Researchers in the College of Agriculture, Health and Natural Resources are working to unlock a decades-long mystery that has hampered development of a walking pneumonia vaccine. Associate Professor Steven Szczepanek and Professor...

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Monoclonal antibodies preserve stem cells in mouse brains, bring promise for future studies

MICHIGAN MEDICINE – UNIVERSITY OF MICHIGAN A new approach to stem cell therapy that uses antibodies instead of traditional immunosuppressant drugs robustly preserves cells in mouse brains and has potential to fast-track trials in humans, a Michigan Medicine study suggests. For this study, researchers used monoclonal antibodies to suppress the immune system in mice and...

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Mindfulness-based stress reduction is as effective as an antidepressant drug for treating anxiety disorders

GEORGETOWN UNIVERSITY MEDICAL CENTER WASHINGTON – A guided mindfulness-based stress reduction program was as effective as use of the gold-standard drug — the common antidepressant drug escitalopram — for patients with anxiety disorders, according to results of a first-of-its-kind, randomized clinical trial led by researchers at Georgetown University Medical Center. The findings appear in JAMA Psychiatry on November...

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Mass General Brigham remote healthcare delivery program improves blood pressure and cholesterol levels

BRIGHAM AND WOMEN’S HOSPITAL Heart disease is the leading cause of death in the United States and around the world. Lowering high blood pressure and cholesterol could help to reduce morbidity and mortality, but frequent in-person visits to measure and manage these readouts can be a burden for patients. A team from Mass General Brigham...

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CHOP researchers find COVID-19 vaccination leads to higher antibody levels than natural infection in both pregnant people and their babies

CHILDREN’S HOSPITAL OF PHILADELPHIA Philadelphia, November 9, 2022—Pregnant people who received one of the mRNA COVID-19 vaccines had 10-fold higher antibody concentrations than those who were naturally infected with SARS-CoV-2, a finding that was also observed in their babies, according to a new study by researchers at Children’s Hospital of Philadelphia (CHOP) and the University...

Tracking malaria parasites in space and time
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Tracking malaria parasites in space and time

INSTITUTO DE MEDICINA MOLECULAR IMAGE: ARTISTIC REPRESENTATION OF THE LIVER AND THE PATHS TAKEN BY THE PARASITES THAT CAUSE MALARIA. CREDIT: HELENA PINHEIRO, IMM Malaria is a devastating disease caused by the Plasmodium parasite. After an infected mosquitos’ bite, the parasites travel to the liver and infect liver cells. This phase of the infection is...

OHSU scientists identify molecule that could help treat Parkinson’s
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OHSU scientists identify molecule that could help treat Parkinson’s

OREGON HEALTH & SCIENCE UNIVERSITY IMAGE: TIANYI MAO, PH.D., AT LEFT, AND HAINING ZHONG, PH.D., SCIENTISTS WITH THE VOLLUM INSTITUTE AT OREGON HEALTH & SCIENCE UNIVERSITY, LED A NEW STUDY FINDING THAT ADENOSINE EFFECTIVELY ACTS AS A BRAKE TO DOPAMINE IN THE BRAIN. CREDIT: OREGON HEALTH & SCIENCE UNIVERSITY Researchers at Oregon Health & Science...

Staphylococcus aureus on the skin of test mice with lupus worsens their symptoms
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Staphylococcus aureus on the skin of test mice with lupus worsens their symptoms

by Bob Yirka , Medical Xpress Scanning electromicrograph of Staphylococcus aureus bacteria. Credit: NIAID A team of researchers at the Tohoku University Graduate School of Medicine, working with a colleague from Japan’s National Cancer Center, has found that the presence of Staphylococcus aureus on the skin of test mice with a lupus-like disease was found...

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Rejuvenated immune cells can improve clearance of toxic waste from brain

WASHINGTON UNIVERSITY SCHOOL OF MEDICINE Alzheimer’s, Parkinson’s and many other neurodegenerative diseases are marked by damaging clusters of proteins in the brain. Scientists have expended enormous effort searching for ways to treat such conditions by clearing these toxic clusters but have had limited success. Now, researchers at Washington University School of Medicine in St. Louis...

HUSH gene-silencing complex contributes to normal brain development and function
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HUSH gene-silencing complex contributes to normal brain development and function

by IMBA- Institute of Molecular Biotechnology of the Austrian Academy of Sciences  Magnification of the mouse cerebellum, the brain region that plays an important role in motor control. Nuclear DNA is shown in blue. In green is the tri-methylation of lysine 9 on histone H3 (H3K9me3), an indicator of silenced heterochromatin. Credit: ©Hagelkruys/IMBA The gene-silencing...