Month: <span>November 2022</span>

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Use of digital devices may affect children’s language development
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Use of digital devices may affect children’s language development

by University of Helsinki Credit: Pixabay/CC0 Public Domain According to a study recently completed at the University of Helsinki, the amount of screen time is linked to language development in children. It was found that the more time preschool-aged children spend alone in front of screens, the poorer their lexical skills and general language level....

A combination of micro and macro methods sheds new light on how different brain regions are connected
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A combination of micro and macro methods sheds new light on how different brain regions are connected

by Lisa Vincenz-Donnelly, Human Brain Project  Detail of a human brain section showing the architecture of fibers down to single axons in the hippocampus, revealed by 3D Polarized Light Imaging. Colors represent 3D fiber orientations highlighting pathways of individual fibers and tracts. Credit: Markus Axer and Katrin Amunts, INM-1, Forschungszentrum Jülich To understand how our...

Gene therapy targeting overactive brain cells could treat neurological disorders
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Gene therapy targeting overactive brain cells could treat neurological disorders

by University College London Schematic of the Activity-dependent Gene Therapy. Credit: Gabriele Lignani A new treatment for neurological and psychiatric diseases, that works by reducing the excitability of overactive brain cells, has been developed by UCL researchers. Many brain diseases, such as epilepsy, are caused by excessive activity of a small number of brain cells. These...

Statistical models show rhythmicity of seizures likely changes with age and common triggers
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Statistical models show rhythmicity of seizures likely changes with age and common triggers

by Mike Williams, Rice University An illustration shows how an electronic diary by patients with epilepsy correlates “attractors” like new medications or illnesses with seizures over time. A study by statisticians at Rice University and the University of California, San Francisco formalizes a process by which patient and doctors might better recognize the signs of...

New biomarker could help diagnose Alzheimer’s disease early
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New biomarker could help diagnose Alzheimer’s disease early

by American Chemical Society Graphical abstract. Credit: ACS Chemical Neuroscience (2022). DOI: 10.1021/acschemneuro.2c00342 A definitive diagnosis of Alzheimer’s disease (AD) was once only possible after someone had died, but recent biomarker studies have led to the development of imaging and spinal fluid tests for those still living. However, the tests can only monitor severe disease, differentiating advanced...

How pathogens hijack the immune system to cause vaccine-enhanced disease
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How pathogens hijack the immune system to cause vaccine-enhanced disease

by Anna Zarra Aldrich, University of Connecticut Vaccination with M. pneumoniae lipoproteins is associated with potent reactivation of inflammatory cytokines responses after challenge. A Illustration of experimental timeline and outcome measures. B Lung lesion scores of vaccinated-then-challenged animals. Bronchoalveolar lavage fluid (BALF) concentrations of C TNF-α, D IL-1β, E IL-6, F IL-17A, and G KC...

Blood cancer research points to new treatment for bone marrow cancer
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Blood cancer research points to new treatment for bone marrow cancer

by University of Virginia Deletion of IL-1R1 preferentially inhibits Jak2V617F mutant hematopoietic stem/progenitor cells. a A scheme on competitive BM transplantation approach to assess the effects of IL-1R1 deletion on Jak2V617F mutant hematopoietic stem/progenitors is depicted. b Percentages of donor-derived (CD45.2+) total, myeloid cells (Gr1+), B cells (B220+), and T cells (TCRβ+) in peripheral blood were measured every 4...

Contactless screening tool could revolutionize chronic wound treatment
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Contactless screening tool could revolutionize chronic wound treatment

by RMIT University Pre-processing of a thermal image collected from a participant: (a) raw image; (b) normalized image; (c) background mask; and (d) masked image or extracted wound bed. Credit: Scientific Reports (2022). DOI: 10.1038/s41598-022-20835-y A thermal-imaging tool to screen for chronic wounds could enable nurses to identify these hard-to-heal sores during the first assessment at a...