CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) IMAGE: NEREA DELEYTO-SELDAS AND ALEJO EFEYAN, IN THE CNIO GARDENS. CREDIT: LAURA LOMBARDIA/ CNIO Researchers from the Spanish National Cancer Research Centre (CNIO) and the IMDEA Food Institute have discovered that those who have a certain version of a gene involved in cell nutrition tend to accumulate less fat....
by Tel-Aviv University A lung with breast cancer metastasis, surrounded by inflammatory complement protein: Cyan: Cell nuclei Red: Complement protein Green: blood vessels. Credit: Lea Monteran A new treatment developed at Tel Aviv University may significantly enhance the efficacy of chemotherapy in breast cancer patients, reducing the risk for lung metastasis following chemo from 52%...
by University of Queensland Credit: Queensland Brain Institute The clean-up of cellular “protein clumps” could prevent the onset of some types of dementia, according to a new study from The University of Queensland. Researchers from the Queensland Brain Institute made the discovery after focusing on the relationship between the enzyme Fyn and the protein Tau...
by University of Calgary Credit: Pixabay/CC0 Public Domain People with inflammatory bowel diseases develop inflammation of the intestine that can cause thickening of the gut wall and life-threatening blockage of the intestinal tube. Twenty to 50 percent of people with Crohn’s disease and ulcerative colitis are affected over their lifetime by this poorly understood condition,...
by American College of Cardiology Credit: Unsplash/CC0 Public Domain Incidence of myocarditis, pericarditis or myopericarditis is two- to threefold higher after a second dose of the Moderna Spikevax COVID-19 vaccine when compared to the Pfizer BioNTech COVID-19 vaccine; however, overall cases of heart inflammation with either vaccine are very rare, according to a study in...
by Ingrid Fadelli, Medical Xpress To characterize aging effect at single cell resolution, Kaya et al. used two different single-cell RNA sequencing (scRNA-seq) methods. For plate-based scRNA-seq (Smart-seq2). They isolated and dissociated grey matter from the frontal cortex and white matter tracts from the corpus callosum as well as the optical tracts and the medial...
by British Medical Journal Picture of the back of the eye showing intermediate age-related macular degeneration. Credit: National Eye Institute Regular use of drugs to lower cholesterol and control type 2 diabetes may lessen the risk of the degenerative eye disease associated with aging, known as AMD, finds a pooled data analysis of the available...
by University of Maryland School of Medicine When the SARS-CoV-2 protein Nsp6 is made in a fruit fly heart (center), the heart has structural defects compared to a normal heart without the viral protein (left). When fruit fly hearts with the viral Nsp6 protein are given the metabolism changing drug 2DG (right), the hearts begin...
by Niigata University Letrozole ameliorates liver fibrosis through the inhibition of the CTGF pathway and 17β-hydroxysteroid dehydrogenase 13 expression. Credit: Niigata University A gene expression-based screening assay using chimeric mice with humanized hepatocytes revealed that letrozole has a modifying effect on fibrosis-related gene expression in the hepatocytes, including YAP, CTGF, TGF-β, and CYP26A1. Because of...
by National Kidney Foundation Credit: Pixabay/CC0 Public Domain In a large cohort of patients with common forms of chronic kidney disease (CKD), researchers found that urine-to-plasma ratio of urea ([U/P]urea) was independently associated with CKD progression and kidney failure. An association of urinary concentrating capacity with CKD progression, independently of glomerular filtration rate (GFR), supports the notion...
