by Chinese Academy of Sciences A, an illustration of SOAP stimulating a neuron with an ultrasound focus delivered via the optoacoustic effect. B, the lateral profile of OFUS without and with presence of a piece of mouse skull. C, representative calcium images of cultured neurons before and after OFUS stimulation. The right panel shows the...
Fecal microbial transplants show lack of predictability when no prior antibiotic treatment is given to recipient
by University of Alabama at Birmingham Credit: Pixabay/CC0 Public Domain A fecal microbial transplant—giving a recipient fecal matter from a donor to change the recipient’s gut microbial community in the colon—has been a successful last resort therapy for people with recurrent Clostridium difficile infection after multiple rounds of suppressive antibiotics have eliminated the recipient microbial...
Infant head-shaping pillows are useless and dangerous to baby, FDA warns
by Cara Murez Infant head-shaping pillows are not approved by the U.S. Food and Drug Administration and should not be used, the agency warned Thursday. The pillows can create an unsafe sleep environment for infants, potentially contributing to the risk of suffocation and death. Marketed as changing an infant’s head shape or symmetry or claiming to...
New type of antibiotic could fight tough-to-treat UTIs
by Cara Murez The world desperately needs new antibiotics to fight infection as bacteria become resistant to existing options. GSK has developed a new antibiotic to treat urinary tract infections (UTIs) that appears to be so effective the pharmaceutical company stopped testing early on the recommendation of independent monitors and plans to submit data to...
MicroRNA can help predict which breast cancer patients are more likely to see their cancer come back
by American College of Surgeons Credit: Pixabay/CC0 Public Domain MicroRNA (miRNA) can be used as a biomarker to predict which patients are likely to face breast cancer recurrence and mortality, according to study results published online ahead of print in the Journal of the American College of Surgeons (JACS). While long-term outcomes have improved for patients...
Antibody treatment tested as new tool against malaria
by Carla K. Johnson This 2014 photo made available by the U.S. Centers for Disease Control and Prevention shows a feeding female Anopheles funestus mosquito. The species is a known vector for malaria. The parasitic disease killed more than 620,000 people in 2020 and caused 241 million cases, mainly in children under 5 in Africa....
Psychedelic ‘magic mushroom’ drug may ease some depression
by Lindsey Tanner Credit: Pixabay/CC0 Public Domain The psychedelic chemical in “magic mushrooms” may ease depression in some hard-to-treat patients, a preliminary study found. The effects were modest and waned over time but they occurred with a single experimental dose in people who previously had gotten little relief from standard antidepressants. The study is part...
If at first… pharma’s most drawn-out development timelines revealed
Jacob Plieth Edwin Elmhirst It took nearly two decades from the start of tremelimumab’s first-in-human study until Astrazeneca saw the drug approved last week as Imjudo. This is undoubtedly a lesson in perseverance, but it does not in fact represent the longest development period of a drug from phase 1 to US approval. That honour,...
Getting a flu vaccine lowers your risk of a STROKE years later, study shows
By CASSIDY MORRISON SENIOR HEALTH REPORTER FOR DAILYMAIL.COM PUBLISHED: 13:40 EDT, 4 November 2022 | UPDATED: 14:05 EDT, 4 November 2022 Getting a flu shot might be more important than ever — a study indicates it also lowers the risk of a stroke years later. Researchers say health officials should push harder for everyone to get routine influenza vaccines rather...
Can MS Be Stopped Early in its Tracks?
Kelli Whitlock Burton October 31, 2022 Dimethyl fumarate (DMF) could delay — or even prevent — clinical symptoms in patients with radiologically isolated syndrome (RIS), the earliest detected pre-clinical phase of multiple sclerosis. Researchers found that DMF reduced the risk of a first acute or progressive event related to CNS demyelination by more than 80% compared with...