by Rob Poole, The Conversation Opioids can cause severe constipation. Credit: Tomas Nevesely/Shutterstock In his new autobiography, Matthew Perry reveals that his colon burst as a result of his addiction to opioid painkillers. The 53-year-old actor, who played Chandler Bing in Friends, was in a coma for two weeks following the incident and had to wear a...
by Karolinska Institutet Cerebrospinal fluid levels of C4A are increased in patients with first-episode psychosis who develop schizophrenia. a Overview of the study design. b In the discovery cohort (KaSP), patients with first-episode psychosis (FEP) who developed schizophrenia (FEP-SCZ; n = 29) displayed significantly higher cerebrospinal fluid (CSF) C4A concentrations as compared to healthy controls (HCs; n = 20)...
by University of Missouri Credit: University of Missouri Monkeypox has infected more than 77,000 people in more than 100 countries worldwide, and—similar to COVID-19—mutations have enabled the virus to grow stronger and smarter, evading antiviral drugs and vaccines in its mission to infect more people. Now, a team of researchers at the University of Missouri...
by Cleveland Clinic Cleveland Clinic-led study identifies blood pressure drug as potential treatment for Black patients with Alzheimer’s disease. Credit: Cleveland Clinic Considering how patients from different ethnic groups respond to the same drug could be crucial to finding new Alzheimer’s disease treatments—a disorder the Alzheimer’s Association previously deemed a “silent epidemic” among Black adults....
by Lauran Neergaard Credit: Unsplash/CC0 Public Domain Pfizer’s updated COVID-19 booster significantly revved up adults’ virus-fighting antibodies, the company said Friday, releasing early findings from a rigorous study of the new shots. Booster doses tweaked to target the most common omicron strain rolled out in early September, and the Food and Drug Administration said the latest...
by Katrin Boes, Max Planck Society Wnt4 expression in islets. a Reporter constructs monitoring Wnt4 expression (Wnt4eGFPCre) and used for lineage tracing (Wnt4eGFPCre; mTmG). Expression pattern of Wnt4 revealed by mGFP immunostaining in Wnt4eGFPCre Tg+; mTmG Tg+ islets at E18.5 (b, c), P0 (d), P5 (e) and 8 weeks (f). DAPI marks the nucleus, Insulin β-cells, Glucagon α cells, as color-encoded....
by Zhejiang University Sleep-wake transition-related firing in the PVT is disrupted by AL HFD feeding. Credit: Zhejiang University Obesity induced by a high-fat diet (HFD) is a growing epidemic and major health concern. While excessive daytime sleepiness (EDS) is a pervasive symptom of HFD-induced obesity, research findings suggest that reduced wakefulness could be improved by...
by Ingrid Fadelli, Medical Xpress Confocal image of the dentate gyrus (cyan), with labelled adult-born dentate granule cells (magenta). Image credit: Katja Hartwich/Stephen McHugh/David Dupret The dentate gyrus (DG) is a region of the mammalian brain known to support the encoding of new memories. This brain region is part of the hippocampal formation, a set...
BETH MOLE – 11/2/2022, 1:27 PM Enlarge / An intensive care nurse cares for a patient suffering from respiratory syncytial virus (RSV), who is being ventilated in the children’s intensive care unit of the Olga Hospital of the Stuttgart Clinic in Germany. Getty | picture alliance As an unusually large and early seasonal surge of RSV cases...
by University of Texas M. D. Anderson Cancer Center Stained images of heart tissues in female and male mice with melanoma, treated with IgG antibodies or immune checkpoint inhibitors (ICI). Credit: Y. Zhang, et al., Science Translational Medicine (2022) A new preclinical study from researchers at The University of Texas MD Anderson Cancer Center and the University...
