Hydration levels, foods, and medications can all change urine color. Certain urine colors may also indicate an underlying medical condition. Urine color can be a useful indicator of how well hydrated a person is. Certain foods and medications may also alter urine color. Some urine color changes may be a sign of an infection or...
New CDC opioid guidelines emphasize flexibility in treating pain
By Andrew Joseph Nov. 3, 2022 Reprints PATRICK SISON/AP Federal health officials on Thursday updated their recommendations for using opioids to treat pain, removing specific dose and duration targets that pain experts said had caused unintended harm. The new guidance, released by the Centers for Disease Control and Prevention, reflects the evolution in thinking of how...
A Gene That Leads to Lupus Might Also Save You From COVID
Tony Ho Tran Deputy Editor, Innovation & Tech Updated Nov. 03, 2022 2:23 PM ET / Published Nov. 03, 2022 2:00 PM ET Yuichiro Chino via Getty Autoimmune disorders cause the body’s own defense system to attack normal, healthy cells. They can also leave people vulnerable to diseases—resulting in more severe and deadly infections. But...
RCSI research discovers new role for blood clotting protein in triggering inflammation
RCSI Research by RCSI University of Medicine and Health Sciences has discovered a new role for the blood clotting protein, von Willebrand Factor (VWF), that could lead to the development of new treatments for patients with inflammatory and blood clotting disorders. Published in Nature Communications, the research finds that VWF plays an important role in regulating...
Senescent cells as vaccines against cancer
INSTITUTE FOR RESEARCH IN BIOMEDICINE (IRB BARCELONA) IMAGE: IMMUNE CELL INFILTRATE (IN DEEP RED) AROUND SENESCENT CANCER CELLS (LARGE NUCLEI MARKED IN BLUE). CREDIT: IRB BARCELONA Researchers at IRB Barcelona report that the induction of senescence in tumour cells strongly stimulates the immune system. Vaccination with senescent cells significantly reduces the development of tumours in...
Research at Jacobs University: Coffee could offer protection from catching COVID-19
JACOBS UNIVERSITY BREMEN GGMBH IMAGE: PROFESSOR NIKOLAI KUHNERT AND HIS TEAM WERE ABLE TO SHOW THAT A COMPOUND IN COFFEE INHIBITS THE INTERACTION BETWEEN THE SPIKE PROTEIN AND THE ACE-2 RECEPTOR. (SOURCE: JACOBS UNIVERSITY) CREDIT: JACOBS UNIVERSITY Could consuming a cup of coffee be an effective way to protect yourself against infection with coronavirus? What...
IU researchers investigate brain’s immune cell response in Alzheimer’s disease
INDIANA UNIVERSITY SCHOOL OF MEDICINE INDIANAPOLIS—Indiana University School of Medicine researchers are investigating how the deficiency of a gene in immune cells can shape the progression of Alzheimer’s disease. The study, published in Molecular Degeneration, found that deleting CX3CR1, a microglial gene associated with neurodegenerative diseases, in Alzheimer’s disease animal models resulted in an aggravated disease...
Researchers studying new way to heal diabetic wounds by activating ‘hidden’ mechanism in the body
by Indiana University School of Medicine Graphical abstract. Credit: Molecular Therapy (2022). DOI: 10.1016/j.ymthe.2022.09.002 Researchers at Indiana University School of Medicine are looking for ways to heal wounds by using a healing protein that is active in fetuses, but largely inactive in adults and absent in diabetic adults. “We already know from previous studies at other institutions...
Scientists test two Alzheimer’s drugs head-to-head in first-ever virtual clinical trial
by Adrienne Berard, Pennsylvania State University The biomarker cascade in AD starts with amyloid beta pathology. This leads to amyloid-related tau pathology, neuronal dysfunction/loss and subsequent cognitive impairment. Credit: PLOS Computational Biology (2022). DOI: 10.1371/journal.pcbi.1010481 An estimated 6.2 million Americans ages 65 and older are living with Alzheimer’s disease. The national Alzheimer’s Association predicts that number to grow to...
Brain changes in autism are far more sweeping than previously known, study finds
by University of California, Los Angeles Credit: Unsplash/CC0 Public Domain Brain changes in autism are comprehensive throughout the cerebral cortex rather than just particular areas thought to affect social behavior and language, according to a new UCLA-led study that significantly refines scientists’ understanding of how autism spectrum disorder (ASD) progresses at the molecular level. The...