by American Heart Association Credit: CC0 Public Domain For children with rare heart conditions such as Kawasaki disease, heart failure or congenital heart defects that increase the risk of blood clots, a daily anti-clotting pill may safely allow them to avoid the frequent injections, blood tests and changes in diet and medication dosage required with...
Do water bottles expire? What you need to know when the power goes out
by Cynthia McCormick Hibbert, Northeastern University Credit: Unsplash/CC0 Public Domain Flashlights and candles aren’t the only things people should have on hand during natural disasters and storms. A food safety plan is a must, says Darin Detwiler, associate teaching professor at Northeastern University. “When we have an earthquake or a storm or a hurricane or a tornado,...
People with binge-eating disorder benefit from specific behavioral therapy and medication
by Christopher Gardner, Yale University Credit: Pixabay/CC0 Public Domain A new Yale study found that patients with binge-eating disorder (BED) and obesity can be helped quickly and benefit significantly from a specific behavioral therapy and a specific medication. The study, published in the American Journal of Psychiatry, tested behavioral weight loss treatment (a behavioral therapy focused on gradual...
Cutting-edge bioengineering for musculoskeletal regeneration
Musculoskeletal injuries and disorders are the leading cause of physical disability worldwide, affecting an estimated 1.7 billion people. A new review paper co-authored by researchers in the Guldberg Lab at the Phil and Penny Knight Campus for Accelerating Scientific Impact provides an overview of the latest technological advances targeting musculoskeletal disorders, including recent efforts in translating state-of-the-art bioengineering approaches...
New approaches to treatment of ALS at the DZNE
DZNE – GERMAN CENTER FOR NEURODEGENERATIVE DISEASES A drug that is used to treat immune diseases could help patients with incurable amyotrophic lateral sclerosis (ALS) in the future: Initial indications suggest that the immune system plays a role in the usually very rapid progression of ALS. In a clinical trial at the DZNE’s Bonn and...
A new therapeutic strategy to improve treatment of aggressive endometrial cancer
UNIVERSITAT AUTONOMA DE BARCELONA Endometrial cancer is the most common type of gynecological cancer and is the fourth most common type of tumor in women in developed countries. Although it has a good prognosis if detected early, advanced and aggressive cases have a high mortality rate and are often resistant to standard chemotherapy treatments. Now,...
The guardian of the (epi-)genome
UNIVERSITY OF KONSTANZ The gene coding for the protein p53 is probably the most important factor in protecting human cells from cancer caused by DNA-damaging agents. The protein allows cells to repair damage to their DNA and thereby prevents the development of cancers, which is why it has been nicknamed “the guardian of the genome”....
Repurposing finds new uses for old medicines
by Vittoria D’alessio, Horizon: The EU Research & Innovation Magazine There are many benefits to repurposing “old” drugs to tackle diseases for which treatment is lacking. Credit: Towfiqu barbhuiya via Unsplash Medicines that have been approved to medicate one ailment are being repurposed to treat others, saving lives and giving fresh hope to millions saddled...
How ‘chameleon cancers’ can change their colors to survive treatment
by Newcastle University A Wright’s stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC BY-SA 3.0 An international team of scientists has uncovered one of the mechanisms explaining how some leukemias evade treatment by changing their appearance and identity. Most children with the common blood cancer B-cell acute lymphoblastic leukemia (ALL)...
Protein kinase CK2 has key role in killer T cells during infection by Listeria monocytogenes
by Jeff Hansen, University of Alabama at Birmingham Electron micrograph of a flagellated Listeria monocytogenes bacterium, Magnified 41,250X. Credit: CDC/public domain The protein kinase CK2 is involved in a wide range of biological processes and cellular functions, including inflammatory responses and pathologies associated with inflammation. Also, its aberrant expression and activity are characteristic of many...