Patricia McKnight November 04, 2022 Women with polycystic ovary syndrome (PCOS) may be at a higher risk of developing pancreatic cancer, say researchers reporting a single-center case-control study. A diagnosis of PCOS was associated with a 1.9-fold higher risk of pancreatic cancer after adjusting for age, race, ethnicity, estrogen level, and diabetes. This is the second study to find such...
Month: <span>November 2022</span>
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Cancer: ‘Single-step’ CRISPR treatment may provide lifelong protection
In a small trial, researchers have used gene-editing technology for the first time to treat breast, colon, and lung cancer in humans. Image credit: Andrew Brookes/Getty Images. For the first time, researchers have used CRISPR technology to substitute genes in patients’ immune cells to treat cancer. Participants included 16 patients with different solid cancers including...
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South Asian people undergo type 2 diabetes remission with low calorie diets
by University of Glasgow Weight change from first TDR visit to final study appointment in 23 participants who commenced TDR using all available data (gray). Overall mean change and 95% (blue) based on a mixed model. Credit: The Lancet Regional Health – Southeast Asia (2022). DOI: 10.1016/j.lansea.2022.100111 People of South Asian ethnicity may be able...
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Investigating plasma to predict COVID-19 progression
by Osaka University Graphic abstract. Credit: Journal of Clinical Immunology (2022). DOI: 10.1007/s10875-022-01386-3 Just as oil is essential to keep a car’s motor running, blood is essential to keep the body functioning. The presence of particular proteins in the plasma, the liquid component of blood, may signal the presence of a disease or indicate the severity of...
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What is a ketamine therapy session like? A Philly-based therapist explains her process
by Aubrey Whelan One 10 ml vial of 1000 mg ketamine. Credit: Psychonaught/Wikipedia Jess Jones, a licensed clinical social worker, treats a number of patients with ketamine-assisted therapy—where clients take ketamine, prescribed by a psychiatrist, in a series of sessions to treat severe depression or other serious mental health issues. Interest in psychedelic-assisted therapies such...
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Could these antiviral pills treat long COVID?
by Lisa M. Krieger Credit: Pixabay/CC0 Public Domain Could Paxlovid solve one of the pandemic’s biggest puzzles? A new study at Stanford University aims to find out. In the nation’s first medical trial of an antiviral strategy to treat long COVID, scientists are testing the drug to see if it helps ease the misery of...
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Protein shapes could indicate Parkinson’s disease
by Peter Rüegg, ETH Zurich Credit: Unsplash/CC0 Public Domain ETH Zurich researchers have found that a set of proteins have different shapes in the spinal fluid of healthy individuals and Parkinson’s patients. These could be used in the future as a new type of biomarker for this disease. Many human diseases can be detected and...
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A possible vaccine against the bacteria that cause UTIs
by Bob Yirka, Medical Xpress Sublingual nanofiber vaccine raises antibody responses against three B cell epitopes with broad expression across UPEC strains.(A) Percentage of clinical UPEC isolates that contain the gene encoding the parent proteins of the pIroN, pIutA, and pIreA epitopes (2). Transmission electron microscopy images of nanofibers composed of (B) PEG-Q11pIreA, (C) PEG-Q11pIutA,...
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New CRISPR gene-editing system can “drag-and-drop” DNA in bulk
By Michael Irving November 24, 2022 PASTE is a new variation on the CRISPR gene-editing system that should be more gentle on the genome Depositphotos A new technique has been added to the CRISPR gene-editing toolbox. Known as PASTE, the system uses virus enzymes to “drag-and-drop” large sections of DNA into a genome, which could help...
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Vaping linked to increased risk of tooth cavities
By Rich Haridy November 24, 2022 New research adds to a small but growing body of study investigating the effects of e-cigarette use on oral health Depositphotos Smoking is no good for your teeth, that is well-known. But what about vaping? New research from Tufts University suggests using e-cigarettes may not be that much better,...