Month: <span>March 2023</span>

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Real-world studies confirm effectiveness of bulevirtide to treat chronic hepatitis D
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Real-world studies confirm effectiveness of bulevirtide to treat chronic hepatitis D

Effect of bulevirtide (BLV) monotherapy 2 mg/day for 48 weeks on HDV RNA levels and ALT levels in 18 patients with HDV-related cirrhosis and clinically significant portal hypertension. Credit: Journal of Hepatology In 2020, bulevirtide (BLV) was conditionally approved for treating chronic hepatitis delta (CHD), an inflammation of the liver caused by hepatitis D virus...

Study shows physical activity prevents, not just delays, cancer recurrence in patients previously treated for colon cancer
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Study shows physical activity prevents, not just delays, cancer recurrence in patients previously treated for colon cancer

PENNINGTON BIOMEDICAL RESEARCH CENTER IMAGE: PENNINGTON BIOMEDICAL RESEARCH CENTER’S DR. JUSTIN BROWN CREDIT: PENNINGTON BIOMEDICAL RESEARCH CENTER BATON ROUGE – Researchers, led by Pennington Biomedical Research Center’s Dr. Justin Brown, have found that physical activity can prevent, and not just delay, cancer recurrence in patients previously treated for colon cancer. “In this observational study of patients with stage III colon...

Can lymph nodes boost the success of cancer immunotherapy?
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Can lymph nodes boost the success of cancer immunotherapy?

Graphical abstract. Credit: Cell (2023). DOI: 10.1016/j.cell.2023.02.021 Cancer treatment routinely involves taking out lymph nodes near the tumor in case they contain metastatic cancer cells. But new findings from a clinical trial by researchers at UC San Francisco and Gladstone Institutes shows that immunotherapy can activate tumor-fighting T cells in nearby lymph nodes. The study, published in...

Immune system cells in the gut linked to stress-induced depression
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Immune system cells in the gut linked to stress-induced depression

by Marisol Martinez,  Johns Hopkins University School of Medicine Illustration of bacteria in the human gut. Credit: Darryl Leja, National Human Genome Research Institute, National Institutes of Health In experiments with mice and humans, a team led by Johns Hopkins Medicine researchers says it has identified a particular intestinal immune cell that impacts the gut microbiome,...

Gout may be caused by deficiency of a protein found in joint fluid
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Gout may be caused by deficiency of a protein found in joint fluid

Scientists are looking into the causes of gout. Design by MNT; Photography by Hulton Archive/Getty Images & Solskin/Getty Images An international research team identified a novel molecular pathway believed to cause gout and its progression to erosion of joint tissue. Researchers believe lubricin, a protein found in joint fluid, may serve as a novel therapeutic...

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Urine Test Predicts Future Bladder Cancer 12 Years Before Symptoms

Neil Osterweil March 13, 2023 A simple urine test for genetic mutations in urine-derived DNA can predict urothelial cancer up to 12 years before patients develop symptoms, an international team of researchers claims. The test, if validated in further studies, has the potential to serve as a cancer screening tool for individuals at elevated risk for bladder...