UNIVERSITY OF CALIFORNIA – SAN DIEGO IMAGE: DON CLEVELAND, PHD, DISTINGUISHED PROFESSOR OF MEDICINE, NEUROSCIENCES AND CELLULAR AND MOLECULAR MEDICINE AT UC SAN DIEGO SCHOOL OF MEDICINE, IS AMONG THE MOST HIGHLY CITED RESEARCHERS IN THE WORLD FOR HIS WORK INVESTIGATING NEURODEGENERATIVE DISEASES. CREDIT: ERIK JEPSEN, UC SAN DIEGO In virtually all persons with amyotrophic...
CINCINNATI CHILDREN’S HOSPITAL MEDICAL CENTER IMAGE: STUDY IN SCIENCE TRANSLATIONAL MEDICINE SHOWS POTENTIAL BENEFIT OF VITAMIN A TREATMENT TO REDUCE SIDE EFFECT RISKS DURING TREATMENT FOR ALL. CREDIT: CINCINNATI CHILDREN’S Consuming a diet rich in vitamin A or its analogs may help prevent children and young adults with acute lymphoblastic leukemia (ALL) reduce their risk...
by University of Helsinki Endogenous CDNF affects the hemorrhagic lesion after ICH. A Photograph of representative films demonstrating temporal changes in CDNF protein in the naive striatum and ICH-affected striatum, at 3 h to 7 days post-ICH in SD rats, which were assessed using Western blotting. B Bar graph showing the relative levels of CDNF protein in the striatum of...
by Delthia Ricks, Medical Xpress Neutralizing activity of vaccinee and convalescent serum samples against wild-type SARS-CoV-2 and Delta and Beta variants.Neutralization was measured against (A) wild-type SARS-CoV-2 strain USA-WA01/2020, (B) a Delta (B.1.617.2) isolate, and (C) a Beta (B.1.351) isolate in a microneutralization assay with authentic SARS-CoV-2. For vaccine groups, n = 35, nBNT162b2 = 20, and nHCS = 18. The exception is n3 μg = 34...
Published: March 13, 2023 Summary Background Neurokinin 3 receptor antagonists are potential non-hormonal therapies for the treatment of vasomotor symptoms in menopausal women as options are scarce for those who cannot or do not want to take hormone therapy. Fezolinetant is one of the first non-hormonal neurokinin 3 receptor antagonists in development for the treatment...
by The Korea Advanced Institute of Science and Technology (KAIST) Results of drug interaction prediction between Paxlovid ingredients and representative approved drugs using DeepDDI2 (670KB) . Credit: The Korea Advanced Institute of Science and Technology (KAIST) Professor Sang Yup Lee’s research team in KAIST’s Department of Biochemical Engineering has developed an advanced AI-based drug interaction prediction technology...
by The Mount Sinai Hospital Daniel Greene, PhD, and colleagues used a computational approach to identify previously unknown genetic causes of three rare diseases: primary lymphedema, thoracic aortic aneurysm disease, and congenital deafness. In this microscopy image of cells, a mutated form of a protein called ERG, which is present in some lymphedema patients, is...
by Kumamoto University Credit: Kumamoto University Matcha, a traditional Japanese tea, has been touted for its health benefits—it can boost mood and mental performance in humans and mice alike—but more mechanistic research is required. Hence, researchers from Japan evaluated the anti-depressive effects of Matcha tea powder in mice. The powder activates dopaminergic neural circuits and...
by Weill Cornell Medical College A transplanted pseudoislet made from CD63hi beta cells. Credit: Weill Cornell Medicine Multiple types of beta cells produce insulin in the pancreas, helping to balance blood sugar levels. Losing a particularly productive type of beta cell may contribute to the development of diabetes, according to a new study by Weill...
by Elsevier Intracranial recording electrodes sample depression-relevant prefrontal regions. (A-C) Frontal views of the reconstructed cortical surface and stereo-EEG recording contacts for Patient 1, Patient 2 and Patient 3, respectively. Stereo-EEG contacts are colored according to the gray matter region sampled: green, anterior cingulate cortex (ACC); red, dorsolateral prefrontal cortex (dlPFC); blue, orbitofrontal cortex (OFC);...
