By Bronwyn Thompson March 16, 2023 Scientists map out mitochondrial structures in lung cancer tumors to find complex, nutrient-specific needs of the cells Depositphotos.com It’s well known that the engine room of cells, the mitochondria, have a key role in fueling cancer growth. Treatments have targeted these microscopic organelles in many ways, including by blocking their...
Mitchel L. Zoler, PhD March 14, 2023 NEW ORLEANS – An investigational, first-in-class agent that delivers a completely new type of intervention to patients with pulmonary arterial hypertension (PAH) scored a clear win in the STELLAR trial, the first to complete among three phase 3 trials that are testing this agent. Sotatercept, administered subcutaneously every 3 weeks for 24...
Max Kozlov The research suggests that the biological effects of sucralose — often used as a sugar substitute — go beyond stimulating taste. Credit: Yon Marsh/Alamy High doses of sucralose — a potent, calorie-free sugar substitute that is 600 times sweeter than sucrose — reduce immune responses in mice, a study has found. The researchers...
Many of us have used Band-Aids to heal a scratch on the skin’s surface, but imagine an internal bandage that can build itself inside our bodies to help repair damaged tissues. Researchers in the lab of Knight Campus assistant professor of bioengineering Gabriella Lindberg are exploring this possibility for cartilage regeneration. The research is detailed in the paper “3D-Bioassembly of VH-Spheroids for Cartilage...
An interdisciplinary collaboration 10 years in the making used a materials science approach to “fingerprint” the calcium mineral deposits known as microcalcifications that reveal pathological clues to the progression of breast cancer and potentially other diseases. The group’s paper, “Biomineralogical Signatures of Breast Microcalcifications,” published in Science Advances. The lead author is postdoctoral researcher Jennie Kunitake, Ph.D....
UNIVERSITY OF NORTH CAROLINA HEALTH CARE VIDEO: UNC HOSPITALS AND UNC SCHOOL OF MEDICINE LEAD NATIONAL RESEARCH AND FDA-APPROVED USE OF FOCUSED ULTRASOUND TO HELP INDIVIDUALS WITH PARKINSON’S DISEASE. CREDIT: UNC DEPARTMENT OF NEUROSURGERY CHAPEL HILL, NC – In a study published in the New England Journal of Medicine co-authored by Vibhor Krishna, MD, associate professor of...
HUMAN BRAIN PROJECT New research by the Human Brain Project has found that in the brains of patients with epilepsy, changes in large scale neuronal activations can be detected in the brain’s resting state activity, even when no seizure is ongoing. The non-invasive approach could lead to a new method to aid epilepsy diagnostics. Diagnosing epilepsy can...
AMERICAN CHEMICAL SOCIETY IMAGE: PROTEINS THAT GLOW BRIGHT BLUE OR GREEN, AS PICTURED HERE, COULD MAKE DISEASE DIAGNOSIS QUICKER AND EASIER. CREDIT: MAARTEN MERKX Despite recent advancements, many highly sensitive diagnostic tests for viral diseases still require complicated techniques to prepare a sample or interpret a result, making them impractical for point-of-care settings or areas...
UNIVERSITY OF MISSOURI-COLUMBIA New research from the University of Missouri School of Medicine has established a link between western diets high in fat and sugar and the development of non-alcoholic fatty liver disease, the leading cause of chronic liver disease. The research, based in the Roy Blunt NextGen Precision Health Building at MU, has identified the western diet-induced microbial and...
UNIVERSITY OF CALIFORNIA – SAN FRANCISCO Breaking a longstanding impasse in our understanding of olfaction, scientists at UC San Francisco (UCSF) have created the first molecular-level, 3D picture of how an odor molecule activates a human odorant receptor, a crucial step in deciphering the sense of smell. The findings, appearing online March 15, 2023, in Nature, are poised...
