Month: <span>March 2023</span>

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Researchers shed light on role of Tip60 enzyme in genetic disruptions that cause Alzheimer’s disease
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Researchers shed light on role of Tip60 enzyme in genetic disruptions that cause Alzheimer’s disease

by Drexel University PET scan of a human brain with Alzheimer’s disease. Credit: public domain Researchers from Drexel University have uncovered a novel regulatory mechanism in the brain that is essential for making the right kinds of proteins that promote healthy brain function, and its malfunctioning may be an early contributor of the development of Alzheimer’s...

Common dry cleaning chemical linked to Parkinson’s
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Common dry cleaning chemical linked to Parkinson’s

by University of Rochester Medical Center Credit: Unsplash/CC0 Public Domain A common and widely used chemical may be fueling the rise of the world’s fastest growing brain condition—Parkinson’s disease. For the past 100 years, trichloroethylene (TCE) has been used to decaffeinate coffee, degrease metal, and dry clean clothes. It contaminates the Marine Corps base Camp...

Common cold may give children immunity against COVID-19, reveals study
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Common cold may give children immunity against COVID-19, reveals study

by Karolinska Institutet Study outline and mapping of T cell responses against OC43 and SARS-CoV-2. (A) Outline of the study design, cohorts, and methodology created with BioRender.com. Cells were stimulated with 20-mer peptides spanning the spike (S), membrane (M), and nucleocapsid (N) proteins from OC43 and SARS-CoV-2, followed by analysis using IFN-γ FluoroSpot and flow cytometry...

A type of immune cell gives possible explanation for sex differences in pancreatic cancer
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A type of immune cell gives possible explanation for sex differences in pancreatic cancer

by Karolinska Institutet Pancreatic cancer cells (blue) growing as a sphere encased in membranes (red). Credit: National Cancer Institute Immunotherapy is an effective form of therapy for different types of cancer. However, for pancreatic cancer, its effect is limited and differs between men and women. Researchers at Karolinska Institutet have now found a possible explanation for this...

Study shows new way to spur brain immune cells to clear toxic waste linked to Alzheimer’s disease
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Study shows new way to spur brain immune cells to clear toxic waste linked to Alzheimer’s disease

by Nanyang Technological University An image of brain immune cells called microglia (green) clustering around a build-up of toxic beta amyloid (red). Credit: LKCMedicine/NTU Singapore A newly discovered “energy switch” in the immune cells of the brain may lead to the development of drugs for Alzheimer’s disease, the most common form of dementia. Nanyang Technological...

CAR T cell robots based on magnetic-acoustic actuation developed for precise antitumor immunotherapy
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CAR T cell robots based on magnetic-acoustic actuation developed for precise antitumor immunotherapy

by Li Yuan, Chinese Academy of Sciences Schematic illustration of M-CAR T microrobots based on magnetic-acoustic sequential actuation for self-controllable guidance towards solid tumors. Credit: SIAT Although chimeric antigen receptor (CAR) T cell therapy has shown potential in the treatment of hematological malignancies, its application in solid tumors is unsatisfactory due to the harsh physical...

People with personality disorders are more likely to sign up for psychology studies—here’s why that’s a problem
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People with personality disorders are more likely to sign up for psychology studies—here’s why that’s a problem

by Nigel Holt, The Conversation Credit: solarseven/Shutterstock Many psychological studies rely on participants to give up their time to take part in experiments or complete questionnaires. They take part because they get paid or because they are required to as part of their university course. But, beyond this, not much is known about what motivates...

3D-printed insoles measure sole pressure directly in the shoe
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3D-printed insoles measure sole pressure directly in the shoe

by Peter Rüegg, ETH Zurich Credit: ETH Zurich Researchers at ETH Zurich, Empa and EPFL are developing a 3D-printed insole with integrated sensors that allows the pressure of the sole to be measured in the shoe and thus during any activity. This helps athletes or patients to determine performance and therapy progress. In elite sports, fractions...

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Dermavant says Vtama topical cream works in PhIII eczema trial

March 15, 2023 09:01 AM EDT Updated 11:04 AM R&D Kyle LaHucikAssociate Editor Dermavant Sciences said its plaque psoriasis-approved cream Vtama also worked in patients with atopic dermatitis, as the Roivant subsidiary pushes toward a label expansion of the topical. In a 406-patient randomized trial, Dermavant said Vtama met the main goal, leading to a...

Breakthrough ultrasound method can detect tension in human tissue
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Breakthrough ultrasound method can detect tension in human tissue

By Paul McClure March 14, 2023 A new ultrasound method has been developed that can, for the first time, measure tension in human tissues Depositphotos Researchers have developed a new ultrasound method that can, for the first time, measure tension in human tissue, potentially revolutionizing disease diagnosis. An ultrasound device emits high-frequency sound waves towards internal body structures...