by Hokkaido University In mice models with adoptive transfer experimental autoimmune encephalomyelitis, treatment with itaconate (right) greatly ameliorates the effects of the disease, compared to untreated mice . Credit: Kuniyuki Aso, et al. Nature Communications, February 27, 2023 Researchers have revealed the modulatory effect of the anti-inflammatory metabolite itaconate on T helper and T regulatory cells, which...
by Justin Jackson, Phys.org Credit: Unsplash/CC0 Public Domain Scientists from a collection of Chinese research institutions collaborated on a study of organ regeneration in mammals, finding deer antler blastema progenitor cells are a possible source of conserved regeneration cells in higher vertebrates. Published in the journal Science, the researchers suggest the findings have applications in clinical bone repair. With the...
MICHELLE HAMPSON 07 MAR 20233 MIN READ SCIENCE PHOTO LIBRARY/GETTY IMAGES JOURNAL This article is part of our exclusive IEEE Journal Watch series in partnership with IEEE Xplore. When a patient has a blocked artery or blood vessel, a team of surgeons must carefully thread an ultrathin catheter through the person’s blood vessel to reach the lesion...
Could a naturally occurring peptide help tackle obesity-related diseases, including diabetes? Image credit: Spencer Platt/Getty Images. Peptides are smaller versions of proteins that have a range of purposes, such as the potential to reduce the signs of aging, relieve inflammation, or promote muscle growth. In 2015, researchers discovered a type of peptide called PEPITEM, and recognized its function...
by Julie Rafferty, Tufts University Credit: Cell Reports Medicine (2023). DOI: 10.1016/j.xcrm.2023.100957 Researchers at Tufts University School of Medicine and colleagues have identified a small molecule that may help treat people with epilepsy whose condition has become resistant to the benzodiazepine drugs usually used in managing seizures. The research, conducted in laboratory cells and rodents, was published online March...
Sue Hughes March 10, 2023 The suggestion that long-term endurance exercise may lead to a paradoxical increase in coronary atherosclerosis has been raised again by a new study. In the Master@Heart study, lifelong endurance athletes had more coronary plaques, including more noncalcified plaques, than fit and healthy individuals with a similarly low cardiovascular risk profile. The study...
UNIVERSITY OF MALTA IMAGE: STUDY FIRST AUTHOR DR. REBECCA BORG AND LEAD INVESTIGATOR PROF. RUBEN CAUCHI HOLDING A VIAL WITH FRUIT FLIES (PHOTO BY CHRIS SANT FOURNIER). CREDIT: CHRIS SANT FOURNIER University of Malta researchers have discovered a potential new drug target for amyotrophic lateral sclerosis (ALS), according to a new study published in the Neurobiology of Aging journal....
GIFU UNIVERSITY IMAGE: THE MECHANISM OF GIPFA-085-MEDIATED INHIBITION OF DIET-INDUCED OBESITY IN MICE SHOWS THAT GIPS HAVE THERAPEUTIC POTENTIAL IN TREATING OBESITY AND DIABETES CREDIT: TOSHIHIKO YADA FROM GIFU UNIVERSITY The hormone glucose-dependent insulinotropic polypeptide (GIP) is considered obesogenic. In contrast, GIP receptor agonists (GIPRAs) have shown reduced feeding and body weight in an obese...
by Dartmouth College Results of face recognition tests. The left panel shows % correct for Famous Faces, Doppelganger, and Cambridge Face Memory Test. The right panel shows A-Prime for the Faces Old-New Test, with values ranging from chance discrimination (0.5) to perfect discrimination (1.0). Annie’s results are in red; control participant results are gray with...
by Medical College of Georgia at Augusta University Yuqing Huo, MD, PhD, (left) and Qian Ma, PhD. Credit: Michael Holahan, Augusta University The vascular smooth muscle cells that normally give blood vessel walls strength and flexibility proliferate and become destructive in pulmonary hypertension, a typically rapidly progressing condition that makes it hard to get blood...
