by Bill Snyder, Vanderbilt University Seasonality of RSV cases in children hospitalized with lower respiratory tract infection in Buenos Aires between 2014 and 2017. (A) A cumulative bar graph of the number of positive cases of respiratory viruses detected per month per year. Dotted lines represent the minimum and maximum temperatures recorded per month per...
New ultrasound method could lead to easier disease diagnosis
by University of Sheffield Principle of acoustoelastic imaging of stresses.(A) Schematic showing that the principal stresses σ1 and σ3 change the speed of the vertically polarized shear waves. Here, an isotropic material subject to moderate stress is taken as an example. (B) An ultrasonic transducer with the axial direction (z) aligned with the principal direction x3 is used to...
A new immune pathway sheds light on amyotrophic lateral sclerosis
by Children’s Hospital Boston An MRI with increased signal in the posterior part of the internal capsule which can be tracked to the motor cortex consistent with the diagnosis of ALS. Credit: Frank Gaillard/Wikipedia While drugs are on the market to slow the progression of neurodegenerative diseases, there are still no cures. But researchers at Boston Children’s...
Early CTE disease process found to be mechanistically different than what occurs in late stages
by Boston University School of Medicine Sample characteristics for the variables examined in this study. A–C Distribution of total years of play, age at death, and log AT8 histochemical quantification, respectively, for RHI, CTE-L, and CTE-H sample groups. D, E Distribution of age at death for each sample group broken out into risk allele groups for APOE and TMEM106B, respectively. F, G Distribution...
Calcium: A key player for a promising and safe brain treatment?
by Tokyo Medical and Dental University Antisense oligonucleotides for treatments of neurological diseases, directly injected into cerebrospinal fluid in spaces around the brain, may cause side effects, abnormalities of consciousness or motor function. These side effects can be predicted by calcium decrease in neuronal cells. Credit: Department of Neurology and Neurological Science, TMDU A promising therapy...
Scientists discover a new way to prevent secondary breast cancer
by Institute of Cancer Research Credit: Pixabay/CC0 Public Domain Scientists have discovered why breast cancer cells that have spread to the lungs may “wake up” following years of sleep, forming incurable secondary tumors. Their research reveals the mechanism that triggers this breast cancer “time bomb”—and suggests a strategy to defuse it. Patients with estrogen receptor positive (ER+) breast cancer—the most...
Epilepsy could become easier to pinpoint with blood test
by Lund University Interictal and postictal immune protein levels in serum from patients with temporal and frontal lobe seizures and PNES. A-B, interictal IL-6 and ICAM-1 protein levels in patients with TLE, FLE, TLE + PNES, PNES, and controls (CTRL). C–H, interictal compared to postictal protein levels of IL-6, MIP1β, TARC, MDC, IFN-y, ICAM-1at 6–8 h and 24 h...
Research Points to Drug Option for Hair-Pulling and Skin-Picking Disorders
Summary: Memantine, a drug commonly prescribed to treat symptoms of Alzheimer’s disease, reduces symptoms for adults with hair-pulling and skin-picking disorders. Source: University of Chicago New research at the University of Chicago Medicine has found that a drug commonly used to treat symptoms of Alzheimer’s disease effectively reduced symptoms of adults who experience compulsive hair-pulling and skin-picking. Treatment with...
New Drug to Lower Brain Pressure Could Treat Blinding Headaches
Summary: Exenatide, an injectable peptide currently in phase two clinical trials for treating type 2 diabetes, reduces symptoms of Idiopathic Intercranial Hypertension blinding headaches, a new study reports. Source: University of Birmingham Patients with ‘blinding’ headaches known as Idiopathic Intercranial Hypertension (IIH) could be treated with an injectable peptide used for type 2 diabetes, a new trial...
Experimental vaccine reprograms cancer to launch immunotherapy attack
By Michael Irving March 05, 2023 Cancer cells can be converted into cells that help the immune system launch an attack on the disease, according to a new study Depositphotos Scientists have developed a new type of cancer vaccine that shows promise in clearing out leukemia in mice. The technique involves reprogramming cancer cells into...