Month: <span>March 2023</span>

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Magrolimab plus azacitidine results in promising activity in higher-risk MDS patients
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Magrolimab plus azacitidine results in promising activity in higher-risk MDS patients

by H. Lee Moffitt Cancer Center & Research Institute Hemoglobin changes from baseline over time on treatment with magrolimab + azacitidine in patients with HR-MDS (N = 95). Data shown are median (Q1, Q3) change in blood samples drawn before each magrolimab dose. Analysis includes all patients who received at least one dose of magrolimab....

COVID survivors at increased risk of long-term gastrointestinal conditions
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COVID survivors at increased risk of long-term gastrointestinal conditions

BETH MOLE – 3/8/2023, 4:00 PM Enlarge Getty | BSIP118WITH Surviving a bout of COVID-19 can significantly increase the risk of developing a range of long-term gastrointestinal symptoms and conditions—from constipation and diarrhea to chronic acid reflux, pancreatitis, and inflammation of the bile ducts—according to a study published this week in Nature Communications. The study likely confirms what...

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Do Artificial Sweeteners Alter Post-Meal Glucose, Hunger Hormones?

Marlene Busko March 02, 2023 Drinking a no-or low-calorie non-nutritive sweetened (NNS) beverage was no different from drinking water in terms of effect on 2-hour postprandial levels of glucose and hormones related to appetite or food intake. Drinking a sugar-sweetened beverage (SSB), however, had a different effect on postprandial levels of glucose and the hormones insulin, glucagon-like...

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Vitamin D a Viable Strategy for Dementia Prevention?

Megan Brooks March 06, 2023 Vitamin D supplementation has the potential to be a viable dementia prevention strategy, especially when initiated early, new research suggests. In a large prospective cohort study, people who took vitamin D were 40% less likely to develop dementia than peers who did not take vitamin D. The effects of vitamin D were most pronounced...

The role of caffeine in preventing diabetic retinopathy
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The role of caffeine in preventing diabetic retinopathy

By Suchandrima Bhowmik Mar 5 2023 Reviewed by Benedette Cuffari, M.Sc. Diabetic retinopathy (DR) is an ophthalmological complication of diabetes that is the primary cause of vision loss and blindness in this patient population. DR is a frequent microangiopathic complication in Catalonia, Spain, with its incidence expected to increase due to the rise in diabetes,...

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New study: abatacept therapy offers promising results treating juvenile dermatomyositis

GEORGE WASHINGTON UNIVERSITY WASHINGTON (March 7, 2023)–Juvenile dermatomyositis, a rare but often severe and chronic systemic autoimmune disease, includes a large number of patients who are treatment resistant, requiring long term immunosuppressive therapy. A small open-label study published in Arthritis and Rheumatology shows promise using a targeted biologic therapy called abatacept to treat such patients. In the...

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New details on how immune cells ‘see’ and respond to mutations in cancer cells may lead to more targeted and effective immunotherapy

UNIVERSITY OF CALIFORNIA – LOS ANGELES HEALTH SCIENCES For the first time, a research team has identified and analyzed the steps by which immune cells “see” and respond to cancer cells, providing insights into reasons some treatments may be effective for certain patients but not others. The UCLA Jonsson Comprehensive Cancer Center scientists leading the research believe their findings will lead...

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Scientists unearth potential new therapeutic target for inflammatory diseases such as Lupus and sepsis

TRINITY COLLEGE DUBLIN Scientists working in the School of Biochemistry and Immunology in the Trinity Biomedical Sciences Institute at Trinity College Dublin have made an important breakthrough in understanding what goes wrong in our bodies during the progression of inflammatory diseases and – in doing so – unearthed a potential new therapeutic target. The scientists...