by University of Tsukuba Credit: Marko Aliaksandr/Shutterstock The kidneys perform a critical role in the body by removing waste and excess fluid in the form of urine. In a condition known as diabetic nephropathy, complications from diabetes disrupt the ability of the kidneys to function properly. Now, researchers in Japan have shed new light on a potential...
by American College of Cardiology Credit: Pixabay/CC0 Public Domain Patients with pulmonary arterial hypertension (PAH), a severe, progressive condition that affects the heart and lungs, who were treated with the novel first-in-class medication sotatercept on top of existing therapy experienced significant improvements in walking distance via a six-minute walking test—the study’s primary endpoint and a...
by Singapore-MIT Alliance for Research and Technology A confocal microscopy image of macrophages treated with MTX (cyan) that have eaten bacteria (magenta). Credit: Singapore-MIT Alliance for Research and Technology (SMART) Researchers have developed a novel combination therapy using an anticancer agent, mitoxantrone (MTX), together with an antibiotic, vancomycin, for treating bacteria that are resistant to the vancomycin, which...
by Tohoku University Previous (A) and updated circuit diagram (B) of the circuit from the hippocampus to the medial entorhinal cortex. We found that the ventral hippocampus efficiently sends out the information to the neocortex via the medial entorhinal cortex (blue arrows in B). Credit: Shinya Ohara et al. Wanting to better understand how the...
by Graciela Gutierrez, Baylor College of Medicine Atherosclerosis of the heart’s arteries reduces surface area and oxygen carrying capacity. Credit: http://www.scientificanimations.com/Wikimedia Commons, CC BY-SA A new study led by Baylor College of Medicine and presented at the American College of Cardiology’s Annual Scientific Session together with World Congress of Cardiology found that an oral PCSK9 inhibitor called...
by Shu Shu Zheng, RMIT University Freeze-dried roselle flowers were used to extract the antioxidant compounds and organic acids. Credit: RMIT University Antioxidants in the roselle plant have anti-obesity properties that could help in food alternatives to current weight management medications, according to new research. The RMIT study, led by Ph.D. candidate Manisha Singh, investigated how antioxidant...
by Cell Press FGF21 counteracts alcohol intoxication by activating the noradrenergic nervous system. Credit: Cell Metabolism/Choi et al. A hormone called fibroblast growth factor 21 (FGF21) protects mice against ethanol-induced loss of balance and righting reflex, according to a study publishing on March 7 in the journal Cell Metabolism. “We’ve discovered that the liver is not only...
By Paul McClure March 06, 2023 Researchers have developed an ingestible microdevice that can be tracked in 3D as it travels through the gut Depositphotos Researchers in the US have developed a platform that allows wireless ingestible devices to be tracked in 3D as they travels through the gastrointestinal (GI) tract, which may provide a cheaper,...
By Michael Irving March 07, 2023 A scanning electron microscope image of E. coli ensnared in a nanonetNational University of Singapore Bacteria are fast developing resistance to our best antibiotics, potentially ushering in a new “dark age of medicine” where currently treatable infections become lethal once again. Now, scientists at the National University of Singapore...
Ted Bosworth February 27, 2023 WASHINGTON – Late lumen loss (LLL) after percutaneous interventions (PCI) can be reduced significantly by a daily glass of beet juice, according to a phase 2 randomized trial. The protection against LLL, attributed to the nitrate contained in beet juice, was accompanied by a trend for a reduced risk of major adverse...
