Month: <span>March 2023</span>

Home / 2023 / March
Temperature-stable tuberculosis vaccine safe, prompts immune response in first-in-human trial
Post

Temperature-stable tuberculosis vaccine safe, prompts immune response in first-in-human trial

by NIH/National Institute of Allergy and Infectious Diseases Scanning electron micrograph of Mycobacterium tuberculosis bacteria, which cause TB. Credit: NIAID A clinical trial testing a freeze-dried, temperature-stable experimental tuberculosis (TB) vaccine in healthy adults found that it was safe and stimulated both antibodies and responses from the cellular arm of the immune system. The Phase...

Potential treatment of autoimmune diseases revealed in new study
Post

Potential treatment of autoimmune diseases revealed in new study

by Lucy Dickie, Okinawa Institute of Science and Technology Mice that have neuroinflammation caused by autoimmunity were treated with PEP. The results found that PEP-treated mice showed improved signs of recovery, in comparison to mice that weren’t treated with PEP. Credit: Tsung-Yen Huang (OIST) Scientists in Japan have revealed a chemical compound that could be...

Study finds protein in blood believed to be linked to depression
Post

Study finds protein in blood believed to be linked to depression

by Pasteur Institute A small group of neural stem cells isolated from mice and cultured in vitro observed under a confocal microscope. (LaminB1 in green, Sox2 in red) Credit: Perception and Memory Unit—Institut Pasteur The process of aging is often related to the onset of neurological symptoms such as cognitive decline, memory loss or mood...

Scientists transform cancer cells into weapons against cancer
Post

Scientists transform cancer cells into weapons against cancer

by Christopher Vaughan, Stanford University Medical Center Credit: Unsplash/CC0 Public Domain Some cities fight gangs with ex-members who educate kids and starve gangs of new recruits. Stanford Medicine researchers have done something similar with cancer—altering cancer cells so that they teach the body’s immune system to fight the very cancer the cells came from. “This approach could...

Erratic sleep patterns linked to elevated blood pressure in teens with extra belly weight
Post

Erratic sleep patterns linked to elevated blood pressure in teens with extra belly weight

by American Heart Association Credit: CC0 Public Domain Staying awake later into the night and sleeping in on the weekends are hallmarks of adolescent behavior, however, erratic sleep patterns may have consequences for future heart health by increasing blood pressure among teens who have more abdominal fat, according to new research published today in Hypertension,...

Molecular change to immunotherapy antibody could accelerate immune response to cancer
Post

Molecular change to immunotherapy antibody could accelerate immune response to cancer

by Weizmann Institute of Science Tissue sample of a particularly aggressive skin cancer reveals immune cells (yellow) that express on their surfaces a “brake pedal” receptor called FcgIIb (purple); cell nuclei are in blue. Credit: Science Immunology (2023). DOI: 10.1126/sciimmunol.add8005 On the road, putting a foot on the gas or brake pedal controls the car’s speed. This...

Brains with compromised ‘trust settings’ a warning sign of lurking depression
Post

Brains with compromised ‘trust settings’ a warning sign of lurking depression

by Hiroshima University Credit: Andrea Piacquadio/Pexels Just as computer devices acting differently can hint at the possibility of malware lurking in the background, changes in brain patterns that shape trust behavior can warn of depression even if symptoms are still in stealth mode, a study found. Brain scans revealed that shrunken gray matter volumes in...

How an injectable, electrode-forming gel could transform clinical research
Post

How an injectable, electrode-forming gel could transform clinical research

Pictured, the injectable gel being tested on a microfabricated circuit. Image credit: Thor Balkhed. Studying the brain is difficult, and often involves invasive techniques, such as using a probe, to gain information about electrical signaling. This means our understanding of exactly how brain signaling works is limited, which has implications for basic science and medical research....

Polycystic kidney disease: How sugar may be a factor
Post

Polycystic kidney disease: How sugar may be a factor

Researchers say sugar can affect cysts that may be a factor in a common type of kidney disease. Oliver Bunic/Bloomberg via Getty Images New research conducted in a laboratory setting may potentially have significant effects on the management of polycystic kidney disease (PKD), a condition impacting more than 500,000 individuals in the United States. Organoids...

Newly identified personalized immunotherapy combination treats an aggressive form of advanced prostate cancer
Post

Newly identified personalized immunotherapy combination treats an aggressive form of advanced prostate cancer

by University of Chicago Medical Center Credit: Unsplash/CC0 Public Domain Immunotherapies have been successful in treating many cancer conditions; however, not much success has yet been achieved in metastatic castrate-resistant prostate cancer (mCRPC). A study published March 2 in Clinical Cancer Research has revealed new insights into why immunotherapies don’t tend to work as well in prostate cancer....