by Baylor College of Medicine GII.4 capsid protein elicits acidification and endocytosis in HIEs. a Viral replication at 24 h (black dots) compared to bound virus at 1 h (blue dots) and inhibition of replication in the presence of VLPs compared to untreated at 24 h. Replication was quantified using n = 2 independent HIE replicates for the 1 h and n = 3 independent HIE replicates...
Is RNS an effective treatment for epilepsy?
Responsive neurostimulation (RNS) is a treatment option that may help to reduce the frequency of seizures. While it does not cure the condition, it is a generally safe, effective, and reversible option to help manage epilepsy. Epilepsy is a common brain condition that can result in seizures. There are various different types of epilepsy that individuals can experience, as...
Gout: How metabolic syndrome may increase the risk
Researchers say people with metabolic syndrome have a higher risk of gout. Eddie Pearson/Stocksy Metabolic syndrome (MetS) appears to increase the likelihood of several conditions occurring together, such as cardiovascular disease, high cholesterol, obesity, and type 2 diabetes. The syndrome is not a singular, distinct disease, but rather a collection of risk factors that have been...
Gout: Combining 2 existing drugs doubles treatment success in new study
Gout is a form of arthritis that results from excess uric acid in the bloodstream and causes intense pain, swelling, and stiffness around a joint. Doctors often treat severe gout with pegloticase (Krystexxa), a medication that reduces uric acid levels, but the body’s immune response to the drug limits its effects. By combining Krystexxa with...
New screening tool can assess cognition issues in older adults
by Cleveland Clinic Credit: Pixabay/CC0 Public Domain A self-administered screening tool, developed by Cleveland Clinic researchers, can effectively and efficiently assess cognition issues in older adults. A new study found that the simple test taken on a tablet computer before an annual physical is conducive to use in a primary care setting for detecting mild cognitive impairment, early Alzheimer’s...
New options for treating eczema
by Olivia Dimmer, Northwestern University Efficacy End Points A, Least squares (LS) mean (SE) of percentage of body surface area (BSA) affected by atopic dermatitis (AD). B, LS mean (SE) Eczema Area and Severity Index (EASI) score. C, LS mean (SE) Peak Pruritus Numerical Rating Scale (PP-NRS) score. Error bars indicate the SE. qw Indicates...
Free-hand, real-time needle guidance for prostate cancer diagnosis with augmented reality
by SPIE The HoloLens AR system components and workflow. (a) A CIRS 048A multimodality pelvis phantom with patient reference frame attached on the MRI/CT table. Insertion: close up view of front and back of the patient reference frame. (b) A DICOM volume was sent to the AR planning software for segmentation of anatomic features, interventional...
Researchers discover vasculogenic fibroblast, a missing piece in understanding how blood vessels are made
by Indiana University School of Medicine Credit: Pixabay/CC0 Public Domain Researchers from the Indiana Center for Regenerative Medicine and Engineering (ICRME) have identified a new type of cell in the human and mouse body, called the vasculogenic fibroblast, that provides critical insight into how new blood vessels can be made when needed for treatment. Blood...
Seizures can be predicted more than 30 minutes before onset in patients with temporal lobe epilepsy
by University of Texas Health Science Center at Houston (Panel A) Patients with medically refractory temporal lobe epilepsy undergoing stereo-electroencephalography (SEEG) for presurgical workup of epilepsy were included in this study (N=15). (Panel B) Each participant provided informed consent for electrode implantation into the thalamus for research purposes. EEG data from the seizure onset zone...
Non-surgical treatment significantly reduces knee pain for adults, especially those 50 and older
by The Reis Group Credit: Pixabay/CC0 Public Domain Genicular nerve radiofrequency ablation is a minimally invasive treatment for knee pain due to osteoarthritis of the knee, and can significantly reduce pain, especially for adults who are 50 and older, according to new research to be presented at the Society of Interventional Radiology Annual Scientific Meeting in Phoenix,...