by Nagoya University PCoA and tmap plots. a PCoA plot showing the centers of gravity and the standard errors of the overall compositions of gut microbiota in nine disease states. Bray-Curtis distance was used as a distance metric. b An integrated topological map, tmap, showing how close genera, disease states, and clinical features are to...
Can Mediterranean diet help people with MS preserve thinking skills?
by American Academy of Neurology Credit: Pixabay/CC0 Public Domain People with multiple sclerosis (MS) who follow a Mediterranean diet may have a lower risk for problems with memory and thinking skills than those who do not follow the diet, according to a preliminary study released today, March 1, 2023, that will be presented at the...
Study unveils mechanism regulating the transmission of a protein associated with the progression of Parkinson’s disease
by Ingrid Fadelli, Medical Xpress Credit: Zhang et al Proteins, long polymers comprised of smaller constituents known as amino acids, play a crucial role in the functioning of the human body. Over the course of a human’s life, these “strings” of proteins fold into unique 3D structures or conformations, and this folding process affects how...
Peptide breakthrough could mean dementia aid is right under your nose
By Bronwyn Thompson March 01, 2023 An oral or nasal spray delivering peptides to the brain may be able to halt neurodegeneration Depositphotos Scientists have discovered a novel way to halt nerve cell death in the most common forms of motor neuron disease and frontotemporal dementia, which could transform how these neurodegenerative conditions are treated....
How to generate new neurons in the brain
by University of Geneva Newly produced neurons (red) in the dentate gyrus with cell nuclei (blue) and a marker for immature neurons (green). Credit: Knobloch Lab – UNIL Some areas of the adult brain contain quiescent, or dormant, neural stem cells that can potentially be reactivated to form new neurons. However, the transition from quiescence...
Scientists discover how to prevent death of nerve cells in most common forms of MND and dementia
by University of Sheffield Credit: Public Domain Scientists have found a novel way to block the transportation of mutant RNA and subsequent production of toxic repeat proteins that lead to the death of nerve cells in the most common subtypes of motor neuron disease (MND) and frontotemporal dementia (FTD). The new study, conducted by researchers at the...
Depression linked to immune response in some people
by University of Bristol Credit: Pixabay/CC0 Public Domain A link between depression and changes in counts of several types of immune cells in the blood has been revealed by researchers at the University of Bristol’s MRC Integrative Epidemiology Unit. These findings, published in Molecular Psychiatry, suggest that changes to different components of our immune system—both the innate and...
Human feces and urine contain a motherlode of health data: ‘Smart toilets’ detect daily fluctuations, serious disease
by Delthia Ricks, Medical Xpress Credit: Pixabay/CC0 Public Domain A disease-detecting toilet capable of a range of monitoring and surveillance activities could soon be reality, and while the device may test for everything from how fast your urine flows to reporting on your vital signs, some people may be a bit squeamish about daily health...
How Bacteria Invade the Brain
By EKATERINA PESHEVA March 1, 2023 Image: Pepe Gallardo/iStock/Getty Images Plus A new study led by researchers at Harvard Medical School details the step-by-step cascade that allows bacteria to break through the brain’s protective layers — the meninges — and cause brain infection, or meningitis, a highly fatal disease. The research, conducted in mice and published March...
Neuroimmune Modulation for Inflammatory Disease: Interview with Dr. Simhambhatla, President and CEO of SetPoint Medical
FEBRUARY 28TH, 2023 CONN HASTINGS EXCLUSIVE, MEDICINE, NEUROLOGY SetPoint Medical, a medtech company based in California, is developing a neuromodulatory device that is intended to treat rheumatoid arthritis. The overlap between the nervous and immune systems is increasingly appreciated, and this technology aims to capitalize on this to create a new treatment for inflammatory disease. The...