Month: <span>March 2023</span>

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Tissue engineering: Developing bioinspired multi-functional tendon-mimetic hydrogels
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Tissue engineering: Developing bioinspired multi-functional tendon-mimetic hydrogels

by Thamarasee Jeewandara, Phys.org Design and processing of tendon-mimetic anisotropic composite hydrogels (ACHs). (A) Chemical structures of ANF and PVA and their intermolecular hydrogen bonding. (B) Schematics of the processing steps for ACH involving stretching and confined drying for the orientation of nanofiber assembly. (C) SEM images of isotropic ANF-PVA hydrogel (top) and ACH-80 (bottom)....

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Irregular Sleep Tied to Markers of Atherosclerosis

Carolyn Crist February 23, 2023 Irregular sleep — such as inconsistent sleep duration or sleep timing — may increase the risk of developing atherosclerosis among adults older than age 45, a new report suggests. In particular, variation in sleep duration of more than 2 hours per night in the same week was tied to higher rates of...

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Drug Combo Promising in Vascular Cognitive Impairment: LACI-2

Sue Hughes February 13, 2023 A combination of two drugs has shown promising results, including a reduction in cognitive impairment in patients who have had a lacunar stroke, and is seen as a new therapeutic approach for patients with cerebral small vessel disease. The drugs — isosorbide mononitrate and cilostazol — stabilize endothelial function, which is a new therapeutic target for patients...

Children’s bad dreams linked to a higher risk of dementia and Parkinson’s disease in adulthood, finds new study
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Children’s bad dreams linked to a higher risk of dementia and Parkinson’s disease in adulthood, finds new study

by Abidemi Otaiku, The Conversation Credit: Pressmaster/Shutterstock Can children’s dreams foretell events that will happen nearly 40 years into the future? Yes, according to the results of my latest study published in the journal eClinicalMedicine. More specifically, it showed that children who experience regular bad dreams and nightmares between the ages of seven and 11, may...

Researchers develop a more sensitive, rapid at-home COVID-19 test
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Researchers develop a more sensitive, rapid at-home COVID-19 test

by Lori Dajose, California Institute of Technology Graphical abstract. Credit: ACS Infectious Diseases (2023). DOI: 10.1021/acsinfecdis.2c00472 Caltech researchers have developed a new at-home test for COVID-19 that is more than twice as sensitive as current state-of-the-art antigen tests. While the test was developed for COVID-19, the technology can be used as a platform for designing tests to detect other...

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Is the brain wired differently in people with addictions?

Some 10 to 15 percent of people will have a substance abuse problem at some point, making it one of the most common psychiatric disorders. Risks associated with substance abuse include dangerous driving, missed work, problems with depression, anxiety, and health and money problems. Yet people with addictions seem to experience a sort of myopia, getting in...

Aspirin reduces ovarian cancer risk regardless of genetic predisposition
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Aspirin reduces ovarian cancer risk regardless of genetic predisposition

By Paul McClure February 26, 2023 A new study suggests that genetic susceptibility to ovarian cancer does not affect the protective effect of aspirin in reducing ovarian cancer risk Depositphotos Ovarian cancer is a highly fatal type of cancer that can be caused by several genetic factors. A recent study examined whether the protection provided...

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RNA modification ‘pivotal’ for protein linked to neurodegeneration in ALS

MICHIGAN MEDICINE – UNIVERSITY OF MICHIGAN Nearly 100% of cases of amyotrophic lateral sclerosis—the progressive, fatal neurodegenerative disease known as ALS or Lou Gherig’s disease — involve the buildup of a protein called TDP-43. Scientists know that TDP-43, which helps regulate processing of RNA, may be responsible for the death of nerve cells in ALS...

Identification of disease-causing proteins leads to new potential treatments for diseases like diabetes
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Identification of disease-causing proteins leads to new potential treatments for diseases like diabetes

by Queen Mary, University of London Credit: CC0 Public Domain New research has identified hundreds of proteins that might contribute to the onset of common, chronic metabolic diseases such as type 2 diabetes, and consequently pathways to potential treatments. The study, published in Nature Metabolism, was led by an international research team from the Medical Research Council...