Month: <span>March 2023</span>

Home / 2023 / March
A molecular machine’s secret weapon exposed
Post

A molecular machine’s secret weapon exposed

COLD SPRING HARBOR LABORATORY IMAGE: KATARINA MEZE, THE FORMER GRADUATE STUDENT IN THE JOSHUA-TOR LAB WHO LED THIS STUDY, STANDING NEXT TO THE LAB’S CRYO-EM IMAGING MACHINE. THE MACHINE ALLOWS SCIENTISTS TO FREEZE MOLECULES IN PLACE TO STUDY THEIR STRUCTURE AND GEOMETRY. CREDIT: JOSHUA-TOR LAB/CSHL RNAs are having a moment. The foundation of COVID-19 vaccines,...

Psyllium fiber protects against colitis by activating bile acid sensor, biomedical sciences researchers find
Post

Psyllium fiber protects against colitis by activating bile acid sensor, biomedical sciences researchers find

GEORGIA STATE UNIVERSITY IMAGE: ANDREW GEWIRTZ, SENIOR AUTHOR OF THE STUDY AND REGENTS’ PROFESSOR IN THE INSTITUTE FOR BIOMEDICAL SCIENCES AT GEORGIA STATE UNIVERSITY CREDIT: GEORGIA STATE UNIVERSITY ATLANTA — Psyllium fiber protects against ulcerative colitis and suppresses inflammation by activating the bile acid nuclear receptor, a mechanism that was previously unrecognized, according to a new study by...

Poor oral health tied to higher risk for Meniere disease
Post

Poor oral health tied to higher risk for Meniere disease

by Lori Solomon  Poor oral health may increase the incidence of Meniere disease, according to a study published in the January issue of the Journal of Personalized Medicine. Jung-Hyun Park, from Mokdong Hospital in Seoul, South Korea, and colleagues examined the association between oral health and Meniere disease. Participant data were retrieved from the National Health...

Fat tissues can play a protective role against inflammation in the intestine
Post

Fat tissues can play a protective role against inflammation in the intestine

by University of Oxford Credit: CC0 Public Domain A new study in The EMBO Journal has revealed how fat tissues might provide a protective role in intestinal inflammation opening new lines of research into the treatment of inflammatory bowel diseases. A fraction of inflammatory bowel disease (IBD) patients, predominantly those with Crohn’s disease, develop a phenomenon known...

Large study finds that air pollution speeds bone loss from osteoporosis
Post

Large study finds that air pollution speeds bone loss from osteoporosis

by Columbia University Bayesian kernel machine regression univariate exposure-response plots with 95% credible intervals for the effect of each pollutant on the different bone mineral density sites evaluated. Credit: eClinicalMedicine (2023). DOI: 10.1016/j.eclinm.2023.101864 Elevated levels of air pollutants are associated with bone damage among postmenopausal women, according to new research led by scientists at Columbia University Mailman...

HIV drug may be linked to increased risk of hypertension
Post

HIV drug may be linked to increased risk of hypertension

by Boston University Credit: Unsplash/CC0 Public Domain In 2019, the World Health Organization formally recommended the drug dolutegravir (DTG) as the preferred antiretroviral therapy (ART) for people living with HIV in low and middle-income countries (LMICs), citing that it is more effective and tolerable, less costly, and less prone to developing drug resistance than the previously recommended...

When is remdesivir effective for COVID-19?
Post

When is remdesivir effective for COVID-19?

by University of Basel Credit: Unsplash/CC0 Public Domain Remdesivir was one of the first medications approved for treatment of COVID-19. Clinical studies evaluated its effectiveness, but did not generate conclusive results. A new analysis of the study data shows that a specific group of patients benefits the most from the drug. Since the outbreak of the COVID-19...

Post

Meta-Analysis Throws More Shade Aspirin’s Way

Richard Mark Kirkner February 15, 2023 A new meta-analysis has added evidence questioning the utility and efficacy of prophylactic low-dose aspirin for preventing cardiovascular events in people who don’t have atherosclerotic cardiovascular disease (ASCVD), whether or not they’re also taking statins, and finds that at every level of ASCVD risk the aspirin carries a risk of major bleeding that exceeds its...

Post

Hip muscle exercises could help amputees improve functional mobility

UNIVERSITY OF BIRMINGHAM Strengthening hip muscles could be key to improve mobility in people with a below-the-knee amputation, new research has shown. Amputation presents significant mobility challenges to millions of people worldwide. Studies show that only 5 percent of people fitted with a prosthetic limb use it for more than half of their waking hours....