AMERICAN GASTROENTEROLOGICAL ASSOCIATION Bethesda, MD (Feb. 21, 2023) — In new evidence-based guidelines, the American Gastroenterological Association (AGA) recommends non-invasive biomarkers as a first-line strategy for monitoring many patients with ulcerative colitis (UC). These guidelines were published today in Gastroenterology. The AGA guidelines outline use cases for three biomarkers that provide accurate insights into ulcerative colitis disease...
Month: <span>March 2023</span>
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A sight for sore eyes: Anti-VEGF treatment in an ocular model of viral infection
TOKYO MEDICAL AND DENTAL UNIVERSITY IMAGE: (A) MULTI-RECEPTOR MODEL OF THE INITIAL PHASE OF HTLV-1 ENTRY INTO TARGET CELLS. (B) SCHEMATIC REPRESENTATION OF INTERACTIONS BETWEEN VEGF165, HSPG, AND NRP-1. HTLV-1: HUMAN T-CELL LYMPHOTROPIC VIRUS TYPE 1; SU: SURFACE SUBUNIT; HSPG: HEPARAN SULFATE PROTEOGLYCAN; NRP-1: NEUROPILIN-1. CREDIT: DEPARTMENT OF OPHTHALMOLOGY AND VISUAL SCIENCE, TMDU Tokyo, Japan...
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Study finds ‘staggering increase’ in methamphetamine deaths tied to opioid co-use
by Diana Yates, University of Illinois at Urbana-Champaign Crystal methamphetamine. Credit: public domain The U.S. methamphetamine mortality rate increased fiftyfold between 1999 and 2021, with most of the added deaths also involving heroin or fentanyl, researchers report in the American Journal of Public Health. “We looked at trends from 1999 to 2021 and we saw this...
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Clinical trial: Doxycycline does not prevent STIs among cisgender women
by Hennepin Healthcare Research Institute Credit: Unsplash/CC0 Public Domain Researchers from the University of Washington (UW), Kenya Medical Research Institute (KEMRI), and Hennepin Healthcare Research Institute (HHRI) announced results at CROI from a clinical trial demonstrating that doxycycline taken after sex does not prevent bacterial sexually transmitted infections (STIs)—chlamydia or gonorrhea—among cisgender women. The dPEP Kenya Trial was conducted...
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Over 40? Just 20 minutes of daily exercise can keep you out of the hospital
by Lori Solomon If you’re over 40, regular exercise may not only keep you fit—it might keep you out of the hospital, too, a large new study suggests. Researchers found that among nearly 82,000 British adults, those who regularly exercised were less likely to be hospitalized for various health conditions in the coming years. The...
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Diabetes Drug Tied to Lower Dementia Risk
Megan Brooks February 16, 2023 Treatment with the thiazolidinedione pioglitazone may offer the greatest protection against dementia for older adults with newly diagnosed type 2 diabetes mellitus (T2DM) who have a history of stroke or ischemic heart disease, new research suggests. Overall, in a large cohort study from Korea, patients who took pioglitazone were 16% less likely to develop dementia over an...
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Team’s imaging strategy enhances lipedema treatment
by Bill Snyder, Vanderbilt University From left, Paula Donahue, PT, DPT, MBA, Aaron Aday, MD, MSc, and Rachelle Crescenzi, PhD, are part of a multidisciplinary effort at VUMC to improve the diagnosis and treatment of lipedema. Credit: Susan Urmy A unique collaboration between imaging science, vascular medicine and rehabilitation at Vanderbilt University Medical Center is...
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Jury Still Out on Obstructive Sleep Apnea Screening
Megan Brooks November 17, 2022 There remains insufficient evidence to weigh the balance of benefits and harms of screening for obstructive sleep apnea (OSA) among asymptomatic adults and those with unrecognized symptoms, the US Preventive Services Task Force (USPSTF) has concluded in an updated statement. “Obstructive sleep apnea can negatively affect people’s health and quality of life if...
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AHRQ Review Highlights Uncertainty Regarding Sleep Apnea Definitions and Outcomes
Aaron B. Holley, MD January 10, 2023 The Agency for Healthcare Research and Quality (AHRQ) just released a new document on long-term health outcomes in patients with obstructive sleep apnea (OSA). AHRQ is a critically important organization that helps health systems, insurers, and providers develop policies for and approaches to care delivery at the individual and population levels. Its findings tend...
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Verapamil shows beneficial effect on the pancreas in children with newly-diagnosed type 1 diabetes
by Alex Smith, University of Minnesota Medical School Visual Abstract. Effect of Verapamil on Pancreatic Beta Cell Function in Newly Diagnosed Pediatric Type 1 Diabetes. Credit: JAMA (2023). DOI: 10.1001/jama.2023.2064 A University of Minnesota led study published in JAMA shows that verapamil, a drug commonly used to treat high blood pressure and heart conditions, can have a beneficial effect on...