NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY IMAGE: MARIT OTTERLEI (CENTER) IS A PROFESSOR AT THE NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY. A NEW CANCER DRUG DEVELOPED BY HER AND HER COLLEAGUES WILL NOW BE TESTED IN THE USA ON PATIENTS WITH SARCOMA, A TYPE OF CONNECTIVE TISSUE CANCER. IN AUSTRALIA, THE MEDICINE WILL BE TESTED...
GOETHE UNIVERSITY FRANKFURT Nitroxoline is the name of the new drug candidate that could potentially be used to treat mpox. It was identified by scientists at Goethe University and the University of Kent as part of a multi-site study. The results of their research will now allow clinical trials to begin soon. The current mpox outbreak is...
LUND UNIVERSITY Researchers at Lund University Faculty of Medicine have determined a novel mechanism linking the metabolism of ribonucleic acids, RNA, to the development of leukemia in myelodysplastic syndrome patients, MDS. In a study published in the Molecular Cell journal, they explain what makes hematopoietic stem cells acquire malignant traits in cancer. RNA splicing is a major...
by University of Texas Health Science Center at San Antonio Mitochondria in a single heart cell. Mitochondria highlighted in red were exposed to ultraviolet light. Credit: National Heart, Lung and Blood Institute, National Institutes of Health Researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have developed a small-molecule...
by Sylvester Comprehensive Cancer Center Credit: Unsplash/CC0 Public Domain Researchers have shown for the first time exactly how immature neutrophils—white blood cells that are an important part of the immune system—are hijacked by pancreatic cancers to drive immunosuppression and treatment resistance. The study, led by investigators at Sylvester Comprehensive Cancer Center at the University of Miami...
HEFEI INSTITUTES OF PHYSICAL SCIENCE, CHINESE ACADEMY OF SCIENCES IMAGE: BRIEF SCHEMATIC DIAGRAM OF THE DETECTION PRINCIPLE AND METHOD. CREDIT: XU WEI Type 2 diabetes (T2D) accounts for more than 90% of the confirmed cases of diabetes. It has become a common metabolic disease and is expected to affect 380 million worldwide in 2025. At...
by Wiley High grade dysplasia (carcinoma in situ) in the uterine cervix. The abnormal epithelium is extending into a mucus gland to the left of centre. This disease can progress to invasive cancer (squamous cell carcinoma) of the cervix. Credit: Haymanj/public domain Dysregulation of microRNAs, which are molecules involved in controlling gene expression, can promote...
by Wiley Credit: Pixabay/CC0 Public Domain Results from a clinical trial published in the Journal of Internal Medicine reveal several health benefits of moderate salt restriction in patients on standard medical treatment for primary aldosteronism. Primary aldosteronism—a condition in which the adrenal glands make too much of the hormone aldosterone—is a common cause of secondary hypertension. The combination of...
by Kyushu University Myofibroblasts are cells that produce collagen and are key in wound repair. Mechanical stimuli of myofibroblast induces VGLL3 to produce more collagen, resulting in hardening of the extracellular matrix and the tissue. The hardening results in an increase in mechanical stimuli that again induces VGLL3 to produce more collagen. The result is...
UNIVERSITY OF JYVÄSKYLÄ – JYVÄSKYLÄN YLIOPISTO A recent study at the University of Jyväskylä compared the gut microbiota and gut-derived metabolites between healthy controls and individuals with fatty liver. The results revealed that certain microbial metabolites are associated with liver fat content. The fact that the gut microbiota associates with many diseases, has raised the...
