Month: <span>June 2023</span>

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Investigating how robots can prevent isolation of the elderly
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Investigating how robots can prevent isolation of the elderly

by University of Tsukuba Social mediator robot. Credit: University of Tsukuba Social Mediator Robots (SMRs), which facilitate communication by mediating messages among people, are considered to prevent isolation in elderly individuals. To avoid isolation, it is crucial for the elderly to talk about their daily problems to others (self-disclosure). SMRs that support such self-disclosure are being...

Q&A: What role does alternative splicing play in neurodegenerative disease?
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Q&A: What role does alternative splicing play in neurodegenerative disease?

by Iqbal Pittalwala, University of California – Riverside Credit: Pixabay/CC0 Public Domain Alternative splicing, a clever way a cell generates many different variations of messenger RNAs—single-stranded RNAs involved in protein synthesis—and proteins from the same stretch of DNA, plays an important role in molecular biology. Progressing rapidly, the field of alternative splicing is a complex topic...

Meta-analysis explores the mechanism that connects cancer and diabetes
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Meta-analysis explores the mechanism that connects cancer and diabetes

by University of Copenhagen Credit: Pixabay/CC0 Public Domain Back in the 1920s, researchers discovered that cancer patients had sweet-smelling urine. First, the doctors were puzzled, but they soon realized that it was a result of elevated blood sugar levels. “This was one of the first things we learned about cancer patients,” says Associate Professor Lykke Sylow. The sweet-smelling...

Metformin’s role in preventing metabolic syndrome during androgen deprivation therapy
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Metformin’s role in preventing metabolic syndrome during androgen deprivation therapy

by Impact Journals LLC Variable changes in phosphorylation of S6 kinase 1 was observed in both cohorts. Credit: Oncotarget (2023). DOI: 10.18632/oncotarget.28458 A new research paper titled “Utilizing metformin to prevent metabolic syndrome due to androgen deprivation therapy (ADT): a randomized phase II study of metformin in non-diabetic men initiating ADT for advanced prostate cancer” has been published in Oncotarget ....

Can light therapy treat atrial fibrillation?
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Can light therapy treat atrial fibrillation?

by Wiley A 12 lead ECG showing atrial fibrillation at approximately 150 beats per minute. Credit: James Heilman, MD/Wikipedia/CC BY-SA 3.0 New research published in the Journal of Internal Medicine demonstrates that optogenetics—which uses light-sensitive proteins to control the activity of targeted cells—is a promising shock-free approach to treating atrial fibrillation (AF), or an irregular, often rapid heart rate, for...

How do testosterone’s effects on the brain change from adolescence into adulthood?
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How do testosterone’s effects on the brain change from adolescence into adulthood?

by Wiley Credit: Pixabay/CC0 Public Domain Higher testosterone levels during adolescence are associated with increased involvement of the brain’s anterior prefrontal cortex (aPFC) in emotion control, but the opposite effect occurs during adulthood. In a study published in Developmental Science, researchers investigated this switch by conducting brain imaging scans in the same individuals during middle adolescence, late adolescence, and...

Intranasal CRISPR psychotropic reduces anxiety-related behavior in mice
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Intranasal CRISPR psychotropic reduces anxiety-related behavior in mice

by PNAS Nexus Representative, low-field immunofluorescence sagittal image following treatment, fixation in formalin, and immunolabeling using a specific antibody against green-fluorescence protein (GFP). GFP-positive neurons positively transfected with guide RNA were identified in most brain regions including the olfactory bulb (OB), cortex, cerebellum, and numerous sub-cortical areas including the interpeduncular nucleus (IPN), a major connectome...

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Study shows therapeutic potential of HK for treating degenerative rotator cuff injury in humans

Reviewed by Lily Ramsey, LLM Jun 20 2023 The incidence of degenerative rotator cuff injury in the elderly poses a significant economic burden. A novel study by investigators in The American Journal of Pathology, published by Elsevier, has established that mitochondrial sirtuin 3 (SIRT3) activator honokiol (HK) promotes healing of rotator cuff injury in aged...

Nanorobots Release Reactive Oxygen Species to Kill Fungal Biofilms
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Nanorobots Release Reactive Oxygen Species to Kill Fungal Biofilms

JUNE 19TH, 2023 CONN HASTINGS MEDICINE, NANOMEDICINE Researchers at the University of Pennsylvania have developed nanorobots that can travel to the site of a fungal infection under the influence of an external magnetic field, bind to the fungal cells, and then release reactive oxygen species to completely destroy the fungus. The tiny particles are an example...

Everyone’s brain has a pain fingerprint – new research has revealed for the first time
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Everyone’s brain has a pain fingerprint – new research has revealed for the first time

UNIVERSITY OF ESSEX IMAGE: AN EXAMPLE OF A GAMMA OSCILLATION BRAIN PAIN FINGERPRINT CREDIT: UNIVERSITY OF ESSEX New research has revealed everyone’s brain has a ‘pain fingerprint’ that varies from person to person.  The University of Essex-led study, in collaboration with the neuroscience of pain group at the Ludwig Maximilians University of Munich, found fast-oscillating brain waves...