Wild polio has almost been eradicated, but vaccine-derived strains retain the potential to paralyse. Better vaccines have arrived — but they are only part of the answer. The nOPV2 polio vaccine has been administered to more than 650 million children across 30 countries.Credit: Issouf Sanogo/AFP/Getty When smallpox was declared eradicated in 1980, there were hopes...
THE ENDOCRINE SOCIETY CHICAGO—A new Scientific Statement released today by the Endocrine Society highlights the differences between aspects of aging that are normal and sometimes over-treated, and those such as menopausal symptoms and osteoporosis that can be treated and deserve more attention. “Hormones and Aging: An Endocrine Society Scientific Statement,” reviews the current state of...
by Lori Solomon The U.S. Food and Drug Administration approved Linzess (linaclotide) as a once-daily treatment for pediatric patients ages 6 to 17 years with functional constipation. The approval was based on data from 328 participants who were randomly assigned (1:1) to receive Linzess or placebo. A statistically significant benefit and clinically meaningful improvement was seen for...
Reviewed by Megan Craig, M.Sc. Jun 15 2023 Men were significantly more vulnerable than women to overdose deaths involving opioid and stimulant drugs in 2020-2021, according to a new study analyzing death records data from across the United States. The study found that men had a 2–3 times greater rate of overdose mortality from opioids...
Lori Youmshajekian June 09, 2023 The US Food and Drug Administration (FDA) has approved the first waterless cyclosporine-based solution for treating the signs and symptoms of dry eye disease, according to manufacturer Novaliq GmbH. The treatment, Vevye, (topical cyclosporine ophthalmic solution, also formerly known as CyclASol) 0.1%, is a calcineurin inhibitor immunosuppressant. The water-free and nonpreserved solution contains cyclosporine 0.1%, as well as perfluorobutylpentane...
Tyler Patchen News Reporter Pfizer has notified the FDA that there may be an impending shortage of penicillin, citing an increase in syphilis infections and other shortages. In a letter posted to the FDA’s website and dated Monday, the pharma said there is “limited supply” and an “impending stock out situation” for prefilled Bicillin L-A...
F. Perry Wilson, MD, MSCE April 03, 2023 Few conditions have stymied explanation like autism spectrum disorder (ASD). We know that the prevalence has been increasing dramatically, but we aren’t quite sure whether that is due to more screening and awareness or more fundamental changes. We know that much of the risk appears to be genetic, but there may be 1000...
by Niigata University (A) 9.4-T vertical standard-bore super-conducting magnet, (B) The 1H and 23 Na surface coil. Credit: Kidney360 (2023). DOI: 10.34067/KID.0000000000000072 The gold standard test for predicting the onset of diabetic kidney disease is the albuminuria test. However, detecting albuminuria alone has limited sensitivity and specificity in end-stage renal failure with a decreased estimated glomerular filtration rate. This is...
by Cara Murez Men with erectile dysfunction will now have the option of using a topical gel to treat the condition. The U.S. Food and Drug Administration has approved over-the-counter marketing for the product, called Eroxon, as a first-of-its-kind medical product. The British pharmaceutical firm Futura Medical makes the gel. “FDA set a very high standard in evaluating the effectiveness and...
by Lauren Copeland, The Conversation Credit: Yuri A/Shutterstock Have you been feeling persistently sad for weeks or months? Perhaps you’ve been lacking motivation, or feeling irritable, or anxious, or constantly “on edge.” If symptoms like these are causing you concern and affecting your daily life—including your work, social life, or both—you might consider therapy. If you’re experiencing...
