INSTITUT PASTEUR VIDEO: CAR T CELLS ATTACKING A TUMOR, VISUALIZED USING INTRAVITAL IMAGING. LIVE TUMOR CELLS ARE SHOWN IN WHITE, APOPTOTIC TUMOR CELLS IN BLUE AND CAR T CELLS IN GREEN. The aim of immunotherapy strategies is to use cells in the patient’s own immune system to destroy tumor cells. CAR T cell therapy is...
Month: <span>June 2023</span>
Post
The latest weapon against cancer is … a keto diet?
COLD SPRING HARBOR LABORATORY IMAGE: IN MICE WITH PANCREATIC AND COLORECTAL CANCER, KETO DIETS SLOW THE GROWTH OF TUMORS, SEEN HERE IN WHITE, BY A PROCESS CALLED FERROPTOSIS. THIS KILLS THE CANCER CELLS BY CAUSING A LETHAL BUILDUP OF TOXIC FATTY MOLECULES, STAINED RED Dietitians say a keto diet could help you lose up to...
Post
Study brings new understanding of multiple myeloma evolution
Novel observations of earliest precursor stages among notable findings that could help clinicians intervene earlier in patients most likely to progress UNIVERSITY OF TEXAS M. D. ANDERSON CANCER CENTER LINGHUA WANG, M.D., PH.D. CREDIT: THE UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER HOUSTON – A new study by researchers at The University of Texas MD Anderson...
Post
Research brings hope for early treatment of brain degeneration in children with xeroderma pigmentosum
by European Society of Human Genetics Xeroderma pigmentosum (XP) is a rare and devastating genetic disorder characterized by an inability to repair skin damage caused by ultraviolet (UV) light. As a result, patients with XP develop skin cancers, usually in childhood. Once diagnosed, they can be protected by avoiding sunlight (hence sometimes being called “children of...
Post
Study reveals a trio of immune cells vital in response to liver cancer immunotherapy
by The Mount Sinai Hospital The study revealed how certain immune cell interactions in tumors facilitate response to checkpoint blockade, pointing to potential new approaches to cancer immunotherapy. Credit: Magen et al., Nature Medicine Researchers at the Icahn School of Medicine at Mount Sinai have uncovered a trio of immune cells within tumor niches that are associated with...
Post
Research reveals ultra small molecule as a potential new target for Alzheimer’s disease
by Netherlands Institute for Neuroscience – KNAW Increase in microRNA-132 causes microglia to transition from an activated disease-associated state to a more balanced homeostatic state. The exact implications of this will need to be determined through further research. Credit: Netherlands Institute for Neuroscience A new study from the Netherlands Institute for Neuroscience and the VIB-KU Leuven...
Post
Researchers test AI-powered chatbot’s medical diagnostic ability
by Jacqueline Mitchell, Beth Israel Deaconess Medical Center Performance of Generative Pre-trained Transformer 4 (GPT-4) Histogram of GPT-4’s performance. Performance scale scores (Bond et al2): 5 = the actual diagnosis was suggested in the differential; 4 = the suggestions included something very close, but not exact; 3 = the suggestions included something closely related that might have been helpful; 2 = the suggestions included...
Post
Tethering of shattered chromosomal fragments paves way for new cancer therapies
by University of California – San Diego Fragments of micronuclear chromosomal DNA (green) are tethered together in normal conditions (center), but degrading one of the tether proteins prevents this clustering, causing the DNA fragments to disperse (right). Credit: UC San Diego Health Sciences Healthy cells work hard to maintain the integrity of our DNA, but occasionally,...
Post
AI Unlocks Mysteries of Brain Fluid Flow: A Leap Forward in Alzheimer’s Research
Summary: Researchers harnessed the power of artificial intelligence (AI) to measure the fluid flow around the brain’s blood vessels, a major breakthrough with far-reaching implications for treating diseases like Alzheimer’s. The team developed innovative AI velocimetry measurements to calculate this fluid flow accurately. The newly-developed technique combines 2D measurements with physics-informed neural networks to provide high-resolution insights...
Post
New data demonstrates potential role of probiotic supplementation in adults with major depressive disorder
by King’s College London Credit: Unsplash/CC0 Public Domain A new study published 14 June in JAMA Psychiatry has found evidence that supplementing the diet with a probiotic blend containing 14 strains of bacteria can help individuals who are being treated for major depressive disorder with antidepressants. The research, led by the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at...