By Paul McClure June 15, 2023 Researchers have developed a machine-learning model to identify chemicals that may combat aging Depositphotos Researchers have used a machine learning model to identify three compounds that could combat aging. They say their approach could be an effective way of identifying new drugs, especially for complex diseases. Cell division is necessary...
Could Semaglutide Treat Addiction as Well as Obesity?
Marlene Busko June 13, 2023 Could glucagon-like peptide-1 (GLP-1) receptor agonists such as semaglutide — approved as Ozempic to treat type 2 diabetes and as Wegovy to treat obesity, both from Novo Nordisk — also curb addictions and compulsive behaviors? As demand for semaglutide for weight loss grew following approval of Wegovy by the US Food and Drug Administration in 2021, anecdotal reports of...
Cancer drug from Pfizer appears to stop aneurysm growth, opening door to nonsurgical treatment
By Helen Floersh Jun 14, 2023 02:00 Cancer drug from Pfizer appears to stop aneurysm growth, opening door to nonsurgical treatment. Researchers found that a mutation in the gene PDGFRB was present throughout an aneurysm’s tissue layers, which helped explain the mechanics behind its formation. (Getty Images) About five of every 100 people have a...
Could endometriosis be caused by bacteria? Study offers fresh clues
Heidi Ledford Fusobacterium has been linked with endometriosis. Credit: CNRI/SPL Infection by a particular group of bacteria could be linked to endometriosis, a painful condition that affects up to 10% of women and girls of reproductive age. In a study of 155 women in Japan, members of the bacterial genus Fusobacterium were found in the uteruses of...
New images capture unseen details of the synapse
by Mark Michaud, University of Rochester Medical Center See-through 3D model that shows the axon (red), medium spinal motor neuron (green), and astrocyte converging at the synapse (yellow). Credit: Center for Translational Neuromedicine, University of Rochester and University of Copenhagen Scientists have created one of the most detailed 3D images of the synapse, the important juncture...
Editors’ notes New research reveals the start of Huntington’s disease
by Stowers Institute for Medical Research Fluorescence lifetime micrographs of a fluorescently tagged human protein inside yeast cells. Different colors indicate different states of protein aggregation. Credit: Stowers Institute for Medical Research Devastating neurodegenerative diseases like Huntington’s, Alzheimer’s, and Parkinson’s are all associated with protein deposits in the brain, known as amyloid. Despite extensive research investment into the cause and...
Scientists build a new vaccine arsenal to eradicate polio
by University of California, San Francisco Credit: Unsplash/CC0 Public Domain Despite some of the most successful international vaccination campaigns in history, the poliovirus continues to circulate around the world, posing a threat of neurological damage and even paralysis to anyone who is not vaccinated. While the original polio strains, called wildtype, have largely been eliminated, new strains can...
New data demonstrates potential role of probiotic supplementation in adults with major depressive disorder
by King’s College London Credit: Unsplash/CC0 Public Domain A new study published 14 June in JAMA Psychiatry has found evidence that supplementing the diet with a probiotic blend containing 14 strains of bacteria can help individuals who are being treated for major depressive disorder with antidepressants. The research, led by the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at...
Researchers discover how melanoma changes its environment to support metastasis
by Tel-Aviv University Credit: Pixabay/CC0 Public Domain A new study conducted at Tel Aviv University and the Sheba Medical Center reveals how melanoma cancer cells affect their close environment to support their needs—by forming new lymph vessels in the dermis in order to go deeper into the skin and spread through the body. The researchers believe...
‘Viking disease’ hand disorder may come from Neanderthal genes
by Oxford University Press A ring finger locked in a bent position as seen in Dupuytren’s disease, colloquially known as the “Viking disease.” Credit: Hugo Zeberg/ Molecular Biology and Evolution A new paper in Molecular Biology and Evolution shows that a condition known as Dupuytren’s disease is partly of Neanderthal origin. Researchers have long known that the disease was much...