Megan Brooks May 30, 2023 Intravenous ketamine and intranasal esketamine are both equally effective in improving symptoms of treatment-resistant depression (TRD) in adults, but “speed and cost” appear to favor IV ketamine in clinical practice, results of an observational, single-center study show. Because of insurance restrictions on esketamine nasal spray, treatment initiation can take several weeks longer than IV...
Month: <span>June 2023</span>
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Magnesium-Rich Diet Linked to Lower Dementia Risk
Batya Swift Yasgur, MA, LSW March 31, 2023 A magnesium-rich diet has been linked to better brain health, an outcome that may help lower dementia risk, new research suggests. Investigators studied over 6000 cognitively healthy individuals, aged 40-73, and found that those who consumed more than 550 mg of magnesium daily had a brain age approximately 1 year younger...
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How Dreams Reveal Brain Disorders
By Marie-Neige Cordonnier on June 5, 2023 Credit: sdominick/Getty Images For 30 years Isabelle Arnulf, head of the sleep disorders clinic at Pitié-Salpêtrière Hospital in Paris, has studied sleep and its associated disorders. During her career, Arnulf, who is also a professor of neurology at Sorbonne University in France, has researched a broad range of sleep conditions: sleepwalking, rapid eye...
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Alzheimer’s Cure Stuns Scientists Who Create Artificial Solution Alzheimer’s
Story by TeeJay Small • Yesterday 5:33 PM Alzheimer’s Cure Stuns Scientists Who Create Artificial Solution© Provided by Giant Freakin Robot Anew Alzheimer’s cure is currently being developed after initial trials seem to have cured the disease within mice, according to a recent scientific journal published in Biomedcentral. The trials, which were conducted by a team of...
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Liver-targeted non-viral gene therapy gives hope to hemophiliacs
By Paul McClure June 08, 2023 Researchers have used a non-viral approach to gene therapy, injecting DNA directly into the liver as a way of treating hemophilia Depositphotos As a way of treating hemophilia, Japanese researchers have, for the first time, delivered gene therapy directly into the livers of baboons without using a viral carrier. The study’s...
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New links found between personality and cognitive abilities
In a new landmark study, University of Minnesota research shows surprising links between human cognition and personality — pillars of human individuality that shape us and how we interact with the world. Personality influences our actions, emotions and thoughts, defining whether we are extroverted, polite, persistent, curious or anxious. On the other hand, cognitive ability is the...
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Acoustic-Powered Microrobots for Bladder Disease Treatment
JUNE 8TH, 2023 CONN HASTINGS MATERIALS, UROLOGY Engineers at the University of Colorado at Boulder have developed a medical microrobot that is powered by acoustic waves. The tiny devices, which are 20 micrometers wide and considerably smaller than the width of a human hair, can move incredibly fast for their size, achieving a speed of 3...
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New model offers a way to speed up drug discovery
MASSACHUSETTS INSTITUTE OF TECHNOLOGY IMAGE: BY APPLYING A LANGUAGE MODEL TO PROTEIN-DRUG INTERACTIONS, RESEARCHERS CAN QUICKLY SCREEN LARGE LIBRARIES OF POTENTIAL DRUG COMPOUNDS. CREDIT: ISTOCK CAMBRIDGE, MA — Huge libraries of drug compounds may hold potential treatments for a variety of diseases, such as cancer or heart disease. Ideally, scientists would like to experimentally test each...
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Drug to treat cannabis use disorder shows promise in clinical trial
by Columbia University Irving Medical Center Effects of AEF0117 on mood after cannabis smoking in the Phase 2a study. The subscales of the 44-item VAS used to measure precipitated cannabis withdrawal: (a) Irritable, (b) Anxious, and (c) Miserable were also used to measure mood alterations after smoking cannabis. In this context, in the MMRM analysis performed...
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Study uncovers how B cells react to skin cancer
by King’s College London Spatial transcriptomic coupled with high throughput intratumoral antibody repertoire analyses suggest an active but aberrant B cell response. a Representative image of spatial transcriptomic deconvolution of B cells, T cells and B cell germinal center (GC) signatures. Top panels, signature score per spot; bottom panels, binarized values using 50% (B cells and T cells)...