by Columbia University Irving Medical Center Frequency Histogram of the Difference Between the Estimated Posttransplant Survival (EPTS) Scores of the Skipped Candidates and the Ultimate Recipient for Each Declined Offer, by Reason for Organ Offer Decline. Credit: JAMA Network Open (2023). DOI: 10.1001/jamanetworkopen.2023.16936 A kidney from a deceased donor is supposed to be allocated to the top-ranked patient...
by Dana-Farber Cancer Institute Development of the BRCA-mt signature. UMAP representation of BRCA-mt and BRCA-wt samples from all evaluated cohorts without (a) and after (b) batch adjustment (N = 653). Volcano plots showing differentially expressed miRNAs between BRCA-mutated and wild-type samples without (c) and after (d) batch adjustment (N = 521); red markings represent miRNAs with P < 0.01 and FC > 1.5 or <0.66; purple markings denote ones...
by Duke-NUS Medical School Vascularization of human muscle grafts. a Schematic illustration of: (i) CCP generation; (ii) permanent MI infarction; (iii) intramyocardial transplantation of CCP; (iv) post-transplantation MRI and CT scans, and (v) euthanization at 4 or 12 weeks post-transplantation. At 4 weeks, the human grafts showed disorganized staining of b TNNT2 (red) Scale bar = 20 μm, d ACTN2 (red) and MLC2v...
by Gladstone Institutes Katerina Akassoglou (left) and Andrew Mendiola (right) show how blood makes the brain’s immune cells toxic, pointing to new treatments for Alzheimer’s disease and multiple sclerosis. Credit: Michael Short/Gladstone Institutes In patients with neurological diseases like Alzheimer’s disease and multiple sclerosis, immune cells in the brain known as microglia that normally fulfill beneficial...
by University of Gothenburg Graphical abstract. Credit: Journal of Clinical Investigation (2023). DOI: 10.1172/JCI162253 An effective treatment for most stroke victims—even those who, today, are unable to gain access to care within the first few hours. This is the goal of an experimental method that has been tested with great success in an international study headed by the...
JUNE 6TH, 2023 CONN HASTINGS CARDIOLOGY, RADIOLOGY Researchers at the University of California San Diego have created a wearable ultrasound system that can monitor deep tissues, as far as 16.5 cm (6.5 inches) below the surface of the body. Moreover, the team employed a machine learning algorithm to reduce the noise associated with movement, helping to obtain reliable...
FLINDERS UNIVERSITY IMAGE: HUSBAND AND WIFE PROFESSOR SIMON CONN AND DR VANESSA CONN’S TEAM AT THE FLINDERS CENTRE FOR INNOVATION IN CANCER HAS BEEN RESEARCHING THE ROLE OF CIRCULAR RNAS IN DNA DAMAGE AND FORMING CANCER GENES CREDIT: COURTESY FLINDERS FOUNDATION Australian cancer researchers have made an important new connection between a person’s cancer risk...
INSTITUTE FOR RESEARCH IN BIOMEDICINE (IRB BARCELONA IMAGE: IMMUNOFLUORESCENCE STAINING OF IL-17(WHITE) IN AGED MOUSE SKIN CREDIT: IRB BARCELONA A team of researchers from IRB Barcelona and CNAG identifies the IL-17 protein as a determining factor in skin ageing. Blocking the function of IL-17 reduces the pro-inflammatory state and delays the appearance of age-related features...
by University College London Fatigue is the symptom that most significantly impacts the daily lives of long COVID patients, and can affect quality of life more than some cancers, finds a new study led by researchers at UCL and the University of Exeter. The research, published in BMJ Open , examines the impact of long COVID on the...
by University of Connecticut Credit: Pixabay/CC0 Public Domain Prostate cancer is the most common non-skin cancer in men worldwide. According to international estimates about one in six men will get prostate cancer during their lifetime and worldwide, over 375,000 patients will die from it each year. Tumor resistance to current therapies plays an essential role in...
