by Cell Press Credit: Unsplash/CC0 Public Domain Researchers have successfully converted human pluripotent stem cells into purified pituitary cells that aggregated into hormone-secreting organoids. As reported June 8 in the journal Stem Cell Reports, transplantation of these 3D pituitaries into mice with hypopituitarism resulted in long-lasting improvement in levels of adrenocorticotropic hormone (ACTH), which is normally...
by University of Cambridge Credit: Pixabay/CC0 Public Domain A study of the DNA of more than 55,000 people worldwide has shed light on how we maintain healthy blood sugar levels after we have eaten, with implications for our understanding of how the process goes wrong in type 2 diabetes. The findings, published in Nature Genetics, could help...
by NYU Langone Health Atherosclerosis is a condition affecting the cardiovascular system. If atherosclerosis occurs in the coronary arteries (which supply the heart) the result may be angina pectoris, or in worse cases a heart attack. Credit: Wikipedia/CC BY 3.0 An experimental drug already tested as a potential treatment for cancer, lung, and Alzheimer’s disease may...
by Liam Connolly, UC Davis Graphical abstract. Credit: JCI Insight (2023). DOI: 10.1172/jci.insight.167274 Nephrology researchers at UC Davis Health are shining a light on chronic kidney disease (CKD) as they investigate treatment options for impaired physical performance and exercise intolerance in chronic kidney disease patients. Led by Baback Roshanravan, associate professor of medicine and the Paul F. Gulyassy...
BY CLAUDIA LOPEZ LLOREDA Mouse neurons (in magenta) fuse (yellow) when they express the SARS-CoV-2 protein and its receptor.RAMON MARTINEZ-MARMOL Of all of COVID-19’s symptoms, one of the most troubling is “brain fog.” Victims report headaches, trouble concentrating, and forgetfulness. Now, researchers have shown that SARS-CoV-2 can cause brain cells to fuse together, disrupting their communication....
by University of California – San Diego Credit: Unsplash/CC0 Public Domain Inflammasomes make up an intricate system of molecular sensors that our bodies use to sound an alarm when an infection occurs. However, the mechanisms behind these sensors, which initiate responses to threats such as invading pathogens, and how they operate has been an area of...
By Britney Heimuli Jun 8, 2023, 10:37am MST In this photo provided by Duke Health, surgeons Dr. Jacob Schroder, left, and Dr. Zachary Fitch perform a heart transplant at Duke University Hospital in Durham, N.C., in October 2022. Most transplanted hearts are from donors who are brain-dead, but research published by Duke Health on Wednesday, June 7,...
Reuters June 9, 2023 2:16 AM MST Gulab jamuns (traditional Indian sweet) are on display for sale at a sweets shop in Mumbai, India, April 20, 2018. REUTERS/Francis Mascarenhas NEW DELHI, June 9 (Reuters) – Some 11% of Indians are diabetic, a government study found, adding that diabetes, hypertension and obesity are much more common...
by SINTEF Graphical abstract. Credit: Advanced Drug Delivery Reviews (2022). DOI: 10.1016/j.addr.2022.114528 The fact that our immune systems capture and destroy nanoparticles and the drugs they carry has been a problem in the field of nanomedicine for some time. But, in the fight against cancer, researchers are now attempting to exploit this problem to their advantage. Researchers around the world are...
by Lancet Credit: Pixabay/CC0 Public Domain Taking a two-week course of metformin, a safe and affordable diabetes medication after testing positive for SARS-CoV-2 leads to 40% fewer long COVID diagnoses over the following 10 months, compared to individuals taking a placebo, finds a new study published in The Lancet Infectious Diseases journal. The long-term symptoms some people experience...
