by University of California, San Francisco Graphical abstract. Credit: JAMA Internal Medicine (2023). DOI: 10.1001/jamainternmed.2023.1977 Women have long searched for remedies for the bothersome hot flashes that often come with menopause. In a novel investigation, researchers at UC San Francisco tested the benefits of continuously wearing a nitroglycerin patch—an established treatment for chest pain from coronary artery disease—for...
Credit: Wikimedia Commons A treatment that involves genetically modifying the body’s own immune cells has been found to cut the risk of disease progression by 74 percent in people with a rare type of blood cancer, results showed Monday. Ciltacabtagene autoleucel—also known by its trade name Carvykti—was tested in a clinical trial involving 419 patients with multiple...
by University of Freiburg Using genome-wide analysis, the researchers identified 1,299 genetic alterations that impact on metabolites in blood plasma and urine. Shown here are the 282 gene locations where enzymes and transporter proteins that influence metabolism are located. Credit: Anna Köttgen/Universität Freiburg Researchers at the Faculty of Medicine at the University of Freiburg have gained significant new insights...
by Northwestern University Credit: CC0 Public Domain Just as people’s joints can get stiff as they age and make it harder for them to move around, hair follicle stem cells also get stiff, making it harder for them to grow hair, reports a new Northwestern Medicine study. But if the hair follicle’s stem cells are softened, they are...
by Melissa Rohman, Northwestern University Genetic overexpression of Hnf4α2 in osteoblasts prevents bone loss in mice with chronic kidney disease. Microtomography analysis of femur cortical bone at metaphysis and at midshaft in 20-week-old wild-type mice. Credit: Northwestern University Northwestern Medicine investigators have discovered that the overexpression of a transcription factor prevented bone loss in mouse models...
by Rush University Medical Center INSPIRE is CDC- funded collaboration of eight major academic medical centers seeking to better understand the long-term effects of COVID. Credit: RUSH Production Group The latest data from the nationwide INSPIRE study assessing the long-term symptoms and outcomes of the COVID-19 virus in nearly 6000 participants identifies four clinically distinct symptom...
by Lund University Credit: Pixabay/CC0 Public Domain A common cause of myocardial infarction and stroke is the rupture of atherosclerotic plaques. The exact location of plaque ruptures has previously been unknown, but now researchers at Lund University have mapped this. The research team has also identified an enzyme, a marker, that they hope will help predict who is at risk...
by National Institutes of Health A new imaging technique that combines cutting-edge ultrasound technology with AI can tell whether a thyroid tumor is malignant or not by peering into its microvasulature — a capability that has been out of reach with conventional ultrasound alone. Credit: Dr. Azra Alizad and Dr. Mostafa Fatemi’s research team. National Institutes of Health Researchers have...
by University of Michigan Bisensory treatment device and stimuli. A. The take-home device is displayed with electrical leads (green) and audio lead (black). B. Personalized treatment spectrum example (blue) is calculated as a subject’s tinnitus likeness (red) set at 40 dB above the subject’s hearing threshold (black) in dB SPL. C. Treatment stimulus: Sample stimulus waveform...
by Ryn Thorn, Medical University of South Carolina Bisected and biantennary fucosylated structures are highly expressed in iCCA tumor. Representative images of the relative intensity of biantennary fucosylated N-glycan (1809.646 m/z); (A) bisected fucosylated N-glycan (2012.717 m/z); (B) tetraantennary branched N-glycan (2393.840 m/z); (C) high mannose N-glycan (1905.630 m/z); (D) proposed N-glycan structures at the bottom...
