by Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering gastrointestinal oncologist Dr. James Harding. Credit: Memorial Sloan Kettering Cancer Center Bile duct cancers are uncommon and aggressive types of gastrointestinal cancer. They include cholangiocarcinomas, which can form inside or outside of the liver, as well as cancers of the gallbladder, and are highly likely to cause...
by UK Research and Innovation Schematic showing the pore forming reorganization of the mitochondrial surface by Bax during the initial stages of apoptosis determined from this study. Credit: Luke Clifton, STFC, ISIS Neutron and Muon Source Researchers have for the first time characterized a unique molecular mechanism of the early stages of programmed cell death or apoptosis, a...
by NYU Langone Health Spatial transcriptomics faithfully maps gene expression in healthy human skin. Credit: Rochelle L. Castillo, Ikjot Sidhu, Jose U. Scher, and Shruti Naik Beneath and beyond the reddish, flaky lesions that form in the skin of those with psoriasis, mild and severe forms of the disease can be told apart by the activity...
by Justin Jackson, Medical Xpress (a) Percentage Δ-change in C-peptide AUC (0–120 min) for the MMTT comparison between baseline (before treatment) and 12 months after treatment, at the day 372 visit. A comparison of participants treated in part A of the study (dose escalation study) was performed. Participants receiving high-dose ProTrans (n=3) demonstrated a maintenance...
by Ingrid Fadelli, Phys.org (a) Schematic diagram of self-healing mechanism of hydrogel; (b) self-healing rates 243 of hydrogel at different times; (c)Self-healing demonstration process of hydrogel; (d) 244 Self-healing effect of multiple healing with hydrogel. Credit: Wang et al. Recent advancements in the field of electronics have enabled the creation of smaller and increasingly sophisticated...
Walter Alexander June 01, 2023 CHICAGO – The regular use of aspirin or other nonsteroidal anti-inflammatory drugs was found to be associated with a lower risk of early-onset conventional and advanced adenomas. The authors say that aspirin could prove to be an effective strategy in preventing early-onset colorectal cancer cases. “What we have here is a 15% reduction for...
Interview conducted by Danielle Ellis, B.Sc. May 30 2023 Thought LeadersDr. Cameron McAlpine Assistant Professor of Medicine and NeuroscienceIcahn School of Medicine at Mount Sinai To commemorate World Multiple Sclerosis (MS) Day, we spoke to Dr. Cameron McAlpine, an Assistant Professor of Medicine and Neuroscience at the Icahn School of Medicine at Mount Sina, about his latest research that sought to understand...
Resarchers have found new possibilities for targeting cancer genes’ RNA with nature-inspired compounds. The cancer gene MYC drives the unrestrained growth of most human cancers. It has been called the “Mount Everest” of oncological research because of the difficulty of designing medications that can disable it, and the expectation that an effective MYC drug could help so...
MAY 30TH, 2023 CONN HASTINGS GI, MATERIALS, MEDICINE, SURGERY Researchers at MIT have developed smart sutures with a hydrogel coating that contains sensing and drug delivery components, and could even be used to implant therapeutic cells. The sutures are made using pig tissues that have been decellularized with detergents to reduce the possibility that they could provoke...
JUNE 1ST, 2023 CONN HASTINGS GI, MEDICINE Researchers at Florida State University have developed a 3D model that examines how the bacterium Helicobacter pylori moves through viscous fluids. H. pylori can cause gastrointestinal ulcers and even cancer, moving through the intestinal mucus layer to reach the wall of the gut. Using antibiotics can cause side-effects and can contribute to drug resistance,...
