JUNE 1ST, 2023 CONN HASTINGS CARDIOLOGY, DIAGNOSTICS, MATERIALS Researchers at Penn State have developed a low-cost, wearable sensor using pencil-on-paper technology. This approach involves depositing graphite (pencil ‘lead’) on paper that has been treated with sodium chloride, to create a conductive, low-cost sensor. Previously, these researchers had developed such sensors to detect moisture and even used...
UNIVERSITY OF VIRGINIA HEALTH SYSTEM New research suggests that the immune system’s ability to respond to spinal cord injuries diminishes with age – and identifies potential avenues to improve that response and help patients heal. The new findings offer important insights into how the immune system responds to spinal-cord injuries, and why that response becomes blunted with the passing...
UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER IMAGE: UTHSC RESEARCHERS CONTRIBUTED TO THE LANDMARK HUMAN PANGENOME DRAFT REFERENCE, WHICH WAS PUBLISHED ALONGSIDE THEIR BIOLOGICAL DISCOVERY REGARDING A COMMON CHROMOSOMAL ABNORMALITY. CREDIT: COURTESY UTHSC Researchers from the University of Tennessee Health Science Center have made a foundational discovery about chromosome biology through their work on the first-ever human...
by Impact Journals LLC Changes in RNA levels after the depletion of G3BP1 and G3BP2, and AS-treatment in SH-SY5Y. Credit: 2023 Sato et al. A new research paper was published on the cover of Aging, title “Stress granules sequester Alzheimer’s disease-associated gene transcripts and regulate disease-related neuronal proteostasis.” Environmental and physiological stresses can accelerate Alzheimer’s disease (AD) pathogenesis....
by Rachel Gordon, MIT Computer Science & Artificial Intelligence Lab Experimental validation of adDEGs. a. Chromogenic RNAscope for ABCC9 and SLC6A1. Prefrontal cortex brain sections (n = 4 for AD and n = 4 for nonAD) were sectioned at 20 µm (3 images per slide), then stored at -80 °C. Sections were then prepared for RNAscope using the manufacturer’s instructions. Scale...
Reviewed by Danielle Ellis, B.Sc. May 31 2023 Acting as a team, twin stem cells activate the immune system to suppress tumor growth and prolong survival in representative preclinical models. Overall survival for patients with melanoma that has spread to the brain is only four to six months. Immunotherapies, which harness the power of the...
By AMERICAN ACADEMY OF NEUROLOGY JUNE 1, 2023 A new study published in Neurology has found a correlation between severe sleep apnea and lower brain volumes in the medial temporal lobe area, including the hippocampus, in people with amyloid plaques, an early sign of Alzheimer’s disease. This correlation, which could suggest brain cell loss, was not seen...
by Waseda University In a new study by Waseda University researchers, young and middle-aged mice were fed isocaloric diets with varying amounts of protein. Mice consuming moderate amounts of dietary proteins (25% and 35%) exhibited lower blood glucose, and hepatic and plasma lipid levels. Credit: Yoshitaka Kondo from Waseda University As the proverb “You are what...
by American Academy of Sleep Medicine Phototherapy device. Credit: University of Arizona Wearing a phototherapy device that emits near-infrared light is associated with potential therapeutic benefits for sleep and daytime functioning, according to a new study to be presented at the SLEEP 2023 annual meeting. Results show that self-reported, sleep-related symptoms improved after three weeks of treatment. Participants in...
by NIH/National Human Genome Research Institute Fibroblasts, shown in green, are cells that connect tissues and organs in the body and play an important role in healing wounds. Genomic variation in the STAT4 gene causes disorganized fibroblasts that fail to heal wounds properly. The nuclei of the fibroblasts are shown in blue. Credit: Ernesto Del Aguila III, NHGRI...
