by Virginia Tech Brandon Jutras and Kathryn Hayes found new candidates for the treatment of syphilis with several being more effective than the current treatment options. Photo by Max Esterhuizen for Virginia Tech. Credit: Virginia Tech Since 2000, sexually transmitted infection rates have been on the rise. Syphilis, a disease that was nearly eradicated in the...
by Swiss Federal Laboratories for Materials Science and Technology Magnetic nanoparticles (red) bind specifically to the spherical bacteria (yellow) which are about 1 µm in size (electron microscopy digitally colored). Credit: Empa Qun Ren, an Empa researcher, and her team are currently developing a diagnostic procedure that can rapidly detect life-threatening blood poisoning caused by staphylococcus...
by Liu Jia, Chinese Academy of Sciences The proposed model for PHD3-mediated noncanonical CRTC2 hydroxylation-dependent activation of hepatic gluconeogenesis. Targeting PHD3 or CRTC2 hydroxylation may provide novel therapeutic avenues for the treatment of hyperglycemia and type 2 diabetes. Credit: Prof. Li’s team A team led by Prof. Li Yu from the Shanghai Institute of Nutrition and...
by Nina Ambros, University of Toronto Researchers Michael Glogauer, right, and Abdelahhad Barbour, left, work in a dry area of a lab that’s reserved for data analysis. Credit: Jeff Comber Researchers at the University Health Network and University of Toronto have discovered a new biotherapeutic molecule—produced by a strain of oral probiotic bacteria—that kills infectious pathogens while promoting...
by Cell Press Photo of iPSCs-derived Motor neurons derived from an ALS patient. Credit: Morimoto et al/Cell Stem Cell Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, is a fatal motor neuron disease that causes people to gradually lose control of their muscles. There is no cure, and current treatments focus on reducing symptoms...
by Children’s Hospital of Philadelphia Credit: Pixabay/CC0 Public Domain Researchers from Children’s Hospital of Philadelphia (CHOP) recently discovered that extremely thorough “deep sequencing” of the genome in tissue samples and cell-free DNA of patients with potentially life-threatening vascular anomalies captured several genetic variants related to disease that were not captured with conventional genetic sequencing methods. More than...
by Wesley Dudgeon, The Conversation Credit: CC0 Public Domain In the past five years, several new drugs have been brought to market that could lead to a profound, if not revolutionary, change in how health care providers—and the public—view weight loss. Three drugs in particular—sold under the brand names Wegovy, Ozempic and Mounjaro—have shown remarkable effects on weight loss in clinical trials. While Wegovy...
by Federico Graciano, Duke-NUS Medical School Credit: Unsplash/CC0 Public Domain Scientists at Duke-NUS Medical School, A*STAR’s Genome Institute of Singapore (GIS), Singapore General Hospital (SGH) and their colleagues in Singapore have used artificial intelligence (AI) to accelerate the discovery of critical biomarkers that can predict, at diagnosis, patients with chronic myeloid leukemia (CML) who will not...
by George Washington University AnX Robotica’s capsule endoscopy system: NaviCam. Credit: AnX Robotica While ingestible video capsule endoscopes have been around for many years, the capsules have been limited by the fact that they could not be controlled by physicians. They moved passively, driven only by gravity and the natural movement of the body. Now, according...
by University of Queensland Credit: The EMBO Journal (2023). DOI: 10.15252/embj.2022112095 Researchers from The University of Queensland have determined how Botox—a drug made from a deadly biological substance—enters brain cells. Professor Frederic Meunier and Dr. Merja Joensuu at UQ’s Queensland Brain Institute have discovered the specific molecular mechanism by which the highly deadly Botulinum neurotoxin type-A, more widely...
